A new kind of mitochondrion
Nature, Published online: 06 November 2024; doi:10.1038/d41586-024-03636-3Mitochondria form two distinct subpopulations enabling them to produce essential cell components and energy, even under nutrient stress.
Nucleosome flipping drives kinetic proofreading and processivity by SWR1
Nature, Published online: 06 November 2024; doi:10.1038/s41586-024-08152-yNucleosome flipping mediates a proofreading and processive mechanism of histone exchange driven by the chromatin remodeller SWR1.
Surprise finding reveals mitochondrial ‘energy factories’ come in two different types
Nature, Published online: 06 November 2024; doi:10.1038/d41586-024-03646-1Mitochondria divide to share the load when nutrients are scarce — plus, how smashing atomic nuclei together helps identify their shapes.
Identification and genetic dissection of convergent persister cell states
Nature, Published online: 06 November 2024; doi:10.1038/s41586-024-08124-2Single-cell transcriptome analyses of growth phases in Escherichia coli identify a distinct transcriptional state occupied by antibiotic-tolerant persisters in w…
Colibactin-driven colon cancer requires adhesin-mediated epithelial binding
Nature, Published online: 06 November 2024; doi:10.1038/s41586-024-08135-zThe oncogenic potential of pks+ Escherichia coli depends critically on bacterial adhesion to host epithelial cells mediated by the type 1 pilus adhesin FimH and …
Coordinated inheritance of extrachromosomal DNAs in cancer cells
Nature, Published online: 06 November 2024; doi:10.1038/s41586-024-07861-8Cooperative species of extrachromosomal DNAs are coordinately inherited through mitotic co-segregation.
Selective ion transport through hydrated micropores in polymer membranes
Nature, Published online: 06 November 2024; doi:10.1038/s41586-024-08140-2A method for design of polymer membranes uses strategically placed pendant groups with specific hydrophobicity to precisely tailor hydrated pore size, with appli…
Autonomous mobile robots for exploratory synthetic chemistry
Nature, Published online: 06 November 2024; doi:10.1038/s41586-024-08173-7A modular autonomous platform for general exploratory synthetic chemistry uses mobile robots to integrate an automated synthesis platform and two analysis platfo…
A cellular basis for mapping behavioural structure
Nature, Published online: 06 November 2024; doi:10.1038/s41586-024-08145-xMice generalize complex task structures by using neurons in the medial frontal cortex that encode progress to task goals and embed behavioural sequences.
Preferential occurrence of fast radio bursts in massive star-forming galaxies
Nature, Published online: 06 November 2024; doi:10.1038/s41586-024-08074-9Analysis of the stellar population properties of 30 host galaxies of fast radio bursts (FRBs) suggests an abundance of FRBs in massive star-forming galaxies, and…