Nature, Published online: 30 October 2024; doi:10.1038/s41586-024-08133-1Experiments using DNA barcoding for lineage tracing in mouse models of colorectal cancer reveal polyclonal origins of premalignant lesions, with a transition to m…
Nature, Published online: 30 October 2024; doi:10.1038/s41586-024-08150-0Colorectal cancer metastasis involves dramatic plasticity and loss of PROX1-mediated repression of non-intestinal lineages.
Nature, Published online: 30 October 2024; doi:10.1038/s41586-024-08137-xWe find that RAS-mutant leukaemia stem cells are resistant to venetoclax, driving clinical resistance and relapse with monocytic features.
Nature, Published online: 30 October 2024; doi:10.1038/s41586-024-08062-zLaser spectroscopy measurements of the fermium isotopic chain show a smooth trend in the nuclear size of heavy actinide elements, and diminishing shell effects on…
Nature, Published online: 30 October 2024; doi:10.1038/s41586-024-08126-0Use of the consensus protein design method facilitated the generation of stable engineered mammalian odorant receptors to gain insight into the molecular properti…
Nature, Published online: 30 October 2024; doi:10.1038/d41586-024-03491-2A heart attack unleashes immune cells that stimulate sleep neurons, leading to restorative slumber.
Nature, Published online: 30 October 2024; doi:10.1038/d41586-024-03561-5In the wake of devastating floods in the South of Brazil, researchers are working out how best to help people — plus, what concerns do Nature’s readers have about…
Nature, Published online: 30 October 2024; doi:10.1038/s41586-024-08108-2We find that leptin-target neurons expressing basonuclin 2 in the arcuate nucleus that acutely suppress appetite by directly inhibiting agouti-related protein neu…
Nature, Published online: 30 October 2024; doi:10.1038/s41586-024-08273-4Autoinhibition of dimeric NINJ1 prevents plasma membrane rupture
Nature, Published online: 30 October 2024; doi:10.1038/s41586-024-08279-yEndogenous self-peptides guard immune privilege of the central nervous system