The seas are on the rise — and that surge is accelerating
Nature, Published online: 31 October 2024; doi:10.1038/d41586-024-03489-wSea-surface data show that the average sea-level rise in 2023 was more than double that in 1993.
Hidden players: the bacteria-killing viruses of the gut microbiome
Nature, Published online: 31 October 2024; doi:10.1038/d41586-024-03532-wViruses known as bacteriophages are difficult to study, but they are beginning to give up their secrets.
Daily briefing: Variant of mpox virus is getting better at human-to-human transmission
Nature, Published online: 31 October 2024; doi:10.1038/d41586-024-03583-zAn mpox virus variant appears to be spreading between humans in Central Africa. Plus, we delve into what makes the human brain so special.
How does overeating lead to diabetes? A surge of neurotransmitters
Nature, Published online: 31 October 2024; doi:10.1038/d41586-024-03513-zIn mice, brain signals triggered the release of fatty acids in the liver, which are linked to metabolic disease.
Anti-obesity drug has life-changing benefits for arthritis
Nature, Published online: 30 October 2024; doi:10.1038/d41586-024-03512-0Clinical-trial participants saw their knee pain abate and could engage better with activities that got them up and going.
Ultra-precise 3D maps of cancer cells unlock secrets of how tumours grow
Nature, Published online: 30 October 2024; doi:10.1038/d41586-024-03539-3Charting the evolution of cancer at single-cell resolution could open up avenues for early diagnosis and treatment.
Endogenous self-peptides guard immune privilege of the central nervous system
Nature, Published online: 30 October 2024; doi:10.1038/s41586-024-08279-yEndogenous self-peptides guard immune privilege of the central nervous system
Cell membranes shaped and cut by phase-separated liquid protein condensates
Nature, Published online: 30 October 2024; doi:10.1038/d41586-024-03495-yIntricate molecular machineries, such as the ESCRT protein complexes, are well known for their ability to cut biological membranes. The discovery that membranes c…
Design of customized coronavirus receptors
Nature, Published online: 30 October 2024; doi:10.1038/s41586-024-08121-5A strategy using engineered functional customized viral receptors enables the development of functional infection models for coronaviruses whose native cellular r…
Temporal recording of mammalian development and precancer
Nature, Published online: 30 October 2024; doi:10.1038/s41586-024-07954-4Using a multipurpose, single-cell CRISPR platform, we demonstrate precise timing of tissue-specific cell expansion during mouse embryonic development, unconventio…