Indian Journal of Medical Research
Development of a cost-effective ex vivo lung perfusion system for lung transplantation in India
Background & objectives:
Standard donor lung preservation with cold flush and storage allows up to six hours between retrieval of lungs from the donor and transplantation in the recipient. Ex vivo lung perfusion (EVLP) systems mimic physiological v…
Indian Journal of Medical Research
Safety of autologous intramuscular platelet lysate injections in patients with critical limb ischaemia: A pilot, exploratory study
Background & objectives:
Platelet concentrate contains a rich cocktail of growth factors that support growth and proliferation of cells. The primary goal of this study was to investigate the safety of platelet lysate (PL) in patients with critical …
Indian Journal of Medical Research
HLA-G 3’UTR polymorphisms & response to a yoga-based lifestyle intervention in rheumatoid arthritis: A randomized controlled trial
Background & objectives:
Human leucocyte antigen (HLA)-G plays a vital role in immunomodulation in rheumatoid arthritis (RA). The mounting evidence suggests a link between HLA-G gene polymorphisms, disease susceptibility and methotrexate treatment …
Indian Journal of Medical Research
A clinicoepidemiological profile of lung cancers in India – Results from the National Cancer Registry Programme
Background & objectives:
Lung cancer is a significant public health concern in low- and middle-income countries such as India. The present article describes the epidemiology, and clinical profile of lung cancer in India, based on recent data from t…
Indian Journal of Medical Research
NDM-beta-lactamase-1: Where do we stand?
Multidrug-resistant (MDR) Gram-negative bacilli (GNB) have been playing havoc in the field of nosocomial as well as community-acquired infections. Of particular concern are the carbapenem-resistant GNBs, belonging to Enterobacteriaceae and encoding for…
Indian Journal of Medical Research
Institutional end-of-life care policy for inpatients at a tertiary care centre in India: A way forward to provide a system for a dignified death
India has a high share in the global burden of chronic terminal illnesses. However, there is a lack of a uniform system in providing better end-of-life care (EOLC) for large patients in their terminal stage of life. Institutional policies can be a good…