Indian Journal of Medical Research
High density lipoprotein heterogeneity & function among Indians with coronary artery disease
Background & objectives:
Impaired high density lipoprotein (HDL) functionality has been shown to be associated with cardiovascular disease risk. The study was aimed to identify the alterations in HDL function [antioxidative activity (AOA)] and subf…
Indian Journal of Medical Research
Clinical spectrum & changing presentation of celiac disease in Indian children
Background & objectives:
Celiac disease (CD) is a genetic immune mediated disorder characterised by gluten intolerance. This single centre study, from north India was aimed to assess the clinical, serological and histological profile of CD in a lar…
Indian Journal of Medical Research
BRCA1 promoter methylation & its immunohistochemical correlation in sporadic breast cancer
Background & objectives:
Studies have shown that apart from hereditary breast carcinomas, breast cancer susceptibility gene 1 (BRCA1) mutations conferring to its loss are seen in sporadic breast carcinomas (SBC) as well. The aim of the present stud…
Indian Journal of Medical Research
Molecular detection of drug-resistant Plasmodium falciparum mutants in Assam
Background & objectives:
The spread of drug-resistant Plasmodium falciparum (Pf) poses a serious threat to the control and elimination of malaria. The objective of this study was to detect the molecular biomarkers of antimalarial drug resistance in…
Indian Journal of Medical Research
SARS-CoV-2 antigen detection in deceased bodies: implications for infection prevention
Background & objectives:
High transmissibility of the SARS-CoV-2 has significant implications on healthcare workers’ safety, preservation, handling, transportation and disposal of the deceased bodies. The objective of this study was to detect SARS-…
Indian Journal of Medical Research
Bacterial dissemination in Mycobacterium tuberculosis by CD+ T-cells & proinflammatory cytokines
Background & objectives:
As CD4+ and CD8+ T lymphocyte numbers decline, the conventional, localized forms of tuberculosis shift to the atypical, disseminated forms. Variations in lymphocyte and immune cell expression levels affect how tuberculosis …
Indian Journal of Medical Research
Challenges faced by frontline health managers during the implementation of COVID-19 related policies in India: A qualitative analysis
Background & objectives:
The COVID-19 pandemic exposed the strengths and weaknesses of the healthcare systems across the world. Many directives, guidelines and policies for pandemic control were laid down centrally for its implementation; however, …
Indian Journal of Medical Research
Early phase clinical trials in India: Need & scope
No abstract available