Purpose:
The aim of this study was to report a unique clinical presentation of paraproteinemic keratopathy after a myopic uneventful laser in situ keratomileusis (LASIK) procedure that led to the diagnosis of gammopathy of undetermined significance…
Purpose:
The purpose of this study was to study the incidence, demographic features, clinical course, profiling, and management of uncommon species of Pseudomonas keratitis (other than Pseudomonas aeruginosa) at a tertiary eye care center.
Metho…
Purpose:
The purpose of this systematic review was to investigate knowledge and attitudes toward eye donation and sources of eye donation information among the general population.
Methods:
A search was conducted using MEDLINE through Ovid an…
Purpose:
The corneal endothelium, the innermost layer of the human cornea, exhibits a morphology of predominantly hexagonal cells. These endothelial cells are believed to have limited regeneration capacity, and their density decreases over time. En…
Purpose:
Here, we present the procedure to obtain allogeneic solid platelet-rich plasma (PRP) and its use in a pilot study of patients with persistent neurotrophic epithelial defects.
Methods:
We included 4 eyes of 4 patients with persistent…
Purpose:
Gut microbiome alterations have been associated with various autoimmune diseases. There are limited data, however, on relationships between gut dysbiosis and immune-related dry eye (DE). Our aim was to compare the gut microbiome composition of individuals with early and late markers of Sjögren syndrome (SS) with controls without DE.
Methods:
We compared 20 individuals with positive early markers [antisalivary protein 1 (SP1), antiparotid secretory protein (PSP), anticarbonic anhydrase 6 (CA6) IgG, IgA, and IgM, n = 19)], or late markers (anti-Ro/SS-A and anti-La/SS-B, n = 1) of SS with no comorbid autoimmune diagnoses and 20 age-matched and sex-matched controls. Collected stool samples underwent deep RNA sequencing. The main outcomes measured included gut microbiome composition and diversity.
Results:
A total of 20 cases [Dry Eye Questionnaire-5 15.2 ± 3.4, Ocular Surface Disease Index 55.1 ± 22.8, and Schirmer 7.1 ± 5.2 mm] were compared with 20 controls (Dry Eye Questionnaire-5 4.8 ± 3.8, Ocular Surface Disease Index 14.2 ± 12.3, and Schirmer 20.4 ± 9.2 mm). No differences were observed in α-diversity (P = 0.97) or overall community structure (P = 0.62). Between groups, 32 species were differentially abundant (P
Purpose:
The purpose of this study was to describe a case of monkeypox (MPX)-associated disciform keratitis.
Methods:
This is a case report.
Results:
A 36-year-old male patient presented to the infectious diseases clinic with a 1-week…
Abstract:
Endothelial keratoplasty (EK), including Descemet stripping endothelial keratoplasty and Descemet membrane endothelial keratoplasty, is now the most performed corneal transplant procedure in the United States. Intraocular pressure (IOP) e…
Purpose:
The aim of the study was to present the rates of rejection from 2018 to 2021 and evaluate the purported association between COVID-19 vaccination and corneal graft rejection.
Methods:
Cases of corneal graft rejection diagnosed betwee…