Background/Aims
To investigate the role of Wnt signalling in adipogenesis using an in vitro model of Graves’ orbitopathy (GO).
Methods
Orbital fat was obtained from patients with GO and non-GO participants for primary orbital fibroblast (OF) cu…
Background/aims
Recent research suggests an association between normal-tension glaucoma (NTG) and dementia. This study investigated whether cognitive impairment is more strongly associated with NTG than high tension glaucoma (HTG) using cognitive scre…
Natural language processing (NLP) is a subfield of machine intelligence focused on the interaction of human language with computer systems. NLP has recently been discussed in the mainstream media and the literature with the advent of Generative Pre-tr…
Background
Orbital inflammatory disease (OID) encompasses a wide range of pathology including thyroid-associated orbitopathy (TAO), granulomatosis with polyangiitis (GPA), sarcoidosis and non-specific orbital inflammation (NSOI), accounting for up to …
Purpose
To compare the efficacy and safety of brolucizumab versus aflibercept in eyes with polypoidal choroidal vasculopathy (PCV) over 96 weeks in the HAWK study.
Design
HAWK was a global, 2-year, randomised, double-masked, multicentre phase III tri…
Background
Limited data are available on glaucoma surgical trends in Australia.
Methods
Nationwide study of glaucoma surgery in Australia over 17-year period from 2001 to 2018. The Australian Institute of Health, Welfare and Ageing hospitalisation da…
Aims
To determine the correspondence between GNAQ R183Q (c.548G>A) mutation in abnormal scleral tissue of patients with Sturge-Weber syndrome (SWS) secondary glaucoma and explore the role of GNAQ R183Q in glaucoma pathogenesis.
Methods
Episcleral …
Purpose
To determine the effect of valproic acid (VPA) on bleb morphology and scar characteristics in a rabbit model of minimally invasive glaucoma surgery (MIGS).
Methods
Nine New Zealand white rabbits were subjected to MIGS with intraoperative impl…
Background/aims
To evaluate the time needed for patients with Boston type 1 keratoprosthesis (KPro) to reach their best-corrected visual acuity (BCVA) and all contributing factors.
Methods
We retrospectively reviewed 137 consecutive eyes from 118 pat…
Eye health indicators for universal health coverage: results of a global expert prioritisation process (see page 893) An online prioritisation process among 72 eye health experts from all global regions produced a menu of 22 indicators which can infor…