Centre for Cognitive Science

Monoubiquitination of histone H2B is a crucial regulator of the transcriptome during memory formation [BRIEF COMMUNICATIONS]

Posttranslational modification of histone proteins is critical for memory formation. Recently, we showed that monoubiquitination of histone H2B at lysine 120 (H2Bub) is critical for memory formation in the hippocampus. However, the transcriptome contr…

By Navabpour, S., Farrell, K., Kincaid, S. E., Omar, N., Musaus, M., Lin, Y., Xie, H., Jarome, T. J., ago

Monoubiquitination of histone H2B is a crucial regulator of the transcriptome during memory formation [BRIEF COMMUNICATIONS]

Posttranslational modification of histone proteins is critical for memory formation. Recently, we showed that monoubiquitination of histone H2B at lysine 120 (H2Bub) is critical for memory formation in the hippocampus. However, the transcriptome contr…

By Navabpour, S., Farrell, K., Kincaid, S. E., Omar, N., Musaus, M., Lin, Y., Xie, H., Jarome, T. J., ago

HERV-K (HML-2) Envelope Protein Induces Mitochondrial Depolarization and Neurotoxicity via Endolysosome Iron Dyshomostasis

Human endogenous retroviruses (HERVs) are associated with the pathogenesis of amyotrophic lateral sclerosis (ALS); a disease characterized by motor neuron degeneration and cell death. The HERV-K subtype HML-2 envelope protein (HERV-K Env) is expressed…

By Halcrow, P. W., Quansah, D. N. K., Kumar, N., Steiner, J. P., Nath, A., Geiger, J. D., ago