The cerebellum is crucial for predictive motor control and learning, but growing evidence suggests that it also generates forward models for nonmotor functions. Previous studies have reported periodic neuronal activity in the cerebellar dentate nucleu…
A key function of the brain is to move the body through a rich, complex environment. When rodents engage with their environment, they move their whiskers as they extract tactile information. Even though the study of whisking has a long history, the de…
Interference between visual short-term memory (VSTM) and task-irrelevant sensory distractors is a well-documented phenomenon across a wide range of visual features. Although this sensory–memory interference is believed to result from neural inte…
Decision-making is influenced by both expected rewards and social factors, such as who offers the outcomes. Therefore, although a reward might originally be independent of social factors, the two elements are closely related. However, whether and how …
Odor detection in mammals is primarily mediated by odorant receptors (ORs), the largest family of G-protein-coupled receptors, expressed in olfactory sensory neurons (OSNs; Buck and Axel, 1991). However, most ORs exhibit little or no cell surface expr…
Predictions of future events have a major impact on how we process sensory signals. However, it remains unclear how the brain keeps predictions online in anticipation of future inputs. Here, we combined magnetoencephalography (MEG) and multivariate de…
Understanding speech while ignoring competing speech streams in the surrounding environment is challenging. Previous studies have demonstrated that attention shapes the neural representation of speech features. Attended streams are typically represent…
Orexin (hypocretin) neuropeptides regulate numerous essential functions including sleep/wake state stability and reward processing. Orexin synthesizing neurons respond to drug cues and undergo structural changes following persistent drug exposure. Pos…
In the CA1 hippocampus, pyramidal cells (PCs) can be classified as deep or superficial based on their radial position within the stratum pyramidale. Deep and superficial PCs form biased circuits with perisomatic-targeting PV+ basket cells, but it is u…
How is spatial attention deployed in mental images? Mental imagery is often assumed to share mechanisms with visual perception and visual working memory. Top-down, endogenous spatial attention in both visual perception and working memory modulates beh…