Recordings from Parkinson’s disease (PD) patients show strong beta-band oscillations (13–35 Hz), which can be modulated by deep brain stimulation (DBS). While high-frequency DBS (>100 Hz) ameliorates motor symptoms and reduces beta …
How do the neural representations underlying category learning change as skill develops? We examined perceptual category learning using a prototype learning task known to recruit a corticostriatal system including the posterior striatum, motor cortex,…
The sexual receptivity of female mice, shown as lordosis response, is mainly regulated by estradiol action on estrogen receptor alpha (ERα) and beta (ERβ), depending on the day of the estrous cycle. Previous studies revealed that ERα …
“Trying too hard” can interfere with skilled movement, such as sports and music playing. Postural control can similarly suffer when conscious attention is directed toward it (“conscious movement processing”; CMP). However, the neural mechanisms throug…
The transmission of tau pathology has been proposed as one of the major mechanisms for the spatiotemporal spreading of tau pathology in neurodegenerative diseases. Over the last decade, studies have demonstrated that targeting total or pathological ta…
Spike timing-dependent plasticity (STDP) is a learning rule important for synaptic refinement and for learning and memory during development. While different forms of presynaptic t-LTD have been deeply investigated, little is known about the mechanism…
Healthy and successful living involves carefully navigating rewarding and threatening situations by balancing approach and avoidance behaviors. Excessive avoidance to evade potential threats often leads to forfeiting potential rewards. However, little…
Crowding, the phenomenon of impaired visual discrimination due to nearby objects, has been extensively studied and linked to cortical mechanisms. Traditionally, crowding has been studied extrafoveally; its underlying mechanisms in the central fovea, w…
Like all domains of cognition, language processing is affected by top–down knowledge. Classic evidence for this is missing blatant errors in the signal. In sentence comprehension, one instance is failing to notice word order errors, such as tran…