Journal of Neuroscience current issue
{beta}-arrestins Are Scaffolding Proteins Required for Shh-Mediated Axon Guidance
During nervous system development, Sonic hedgehog (Shh) guides developing commissural axons toward the floor plate of the spinal cord. To guide axons, Shh binds to its receptor Boc and activates downstream effectors such as Smoothened (Smo) and Src fa…