The brain’s activity fluctuations have different temporal scales across the brain regions, with associative regions displaying slower timescales than sensory areas. This hierarchy of timescales has been shown to correlate with both structural brain co…
Regulation of food intake and energy balance is critical to survival. Hunger develops as a response to energy deficit and drives food-seeking and consumption. However, motivations to eat are varied in nature and promoted by factors other than energy d…
Fetal alcohol spectrum disorders (FASDs) are characterized by a range of physical, cognitive, and behavioral impairments. Determining how temporally specific alcohol exposure (AE) affects neural circuits is crucial to understanding the FASD phenotype….
Cerebral amyloid-beta (Aβ) accumulation, a hallmark pathology of Alzheimer’s disease (AD), precedes clinical impairment by two to three decades. However, it is unclear whether Aβ contributes to subtle memory deficits observed during the prec…
Accumulation of astrocytes around β-amyloid (Aβ) plaques is one of the earliest neuropathological changes in Alzheimer’s disease (AD), but the underlying mechanisms and significance remain unclear. Cell adhesion molecule protocadherin-C5 (Pc…
While the brain continues to develop during adolescence, such development may depend on sex-at-birth. However, the elucidation of such differences may be hindered by analytical decisions (e.g., covariate selection to address brain-size differences) an…
Hearing is an active process in which listeners must detect and identify sounds, segregate and discriminate stimulus features, and extract their behavioral relevance. Adaptive changes in sound detection can emerge rapidly, during sudden shifts in acou…
In literate adults, an area along the left posterior fusiform gyrus that is often referred to as the “visual word form area” (VWFA) responds particularly strongly to written characters compared with other visually similar stimuli. Theoretical accounts…
Individuals avoid spending cognitive effort unless expected rewards offset the perceived costs. Recent work employing tasks that provide explicit information about demands and incentives suggests causal involvement of the frontopolar cortex (FPC) in e…
The human hippocampus, essential for learning and memory, is implicated in numerous neurological and psychiatric disorders, each linked to specific neuronal subpopulations. Advancing our understanding of hippocampal function requires computational mod…