European Journal of Medicinal Chemistry

Discovery of triazole tethered thymol/carvacrol-coumarin hybrids as new class of α-glucosidase inhibitors with potent <em>in vivo</em> antihyperglycemic activities

Publication date: Available online 15 November 2023Source: European Journal of Medicinal ChemistryAuthor(s): Atamjit Singh, Karanvir Singh, Kirandeep Kaur, Aman Sharma, Pallvi Mohana, Jignesh Prajapati, Uttam Kaur, Dweipayan Goswami, Saroj Arora, Renu …

By ScienceDirect Publication: European Journal of Medicinal Chemistry, ago

Discovery of novel 3-(1<em>H</em>-pyrazol-4-yl)-1<em>H</em>-indazole derivatives as potent type II TRK inhibitors against acquired resistance

Publication date: Available online 15 November 2023Source: European Journal of Medicinal ChemistryAuthor(s): Qiaohua Qin, Zhiqiang Guo, Shuyu Lu, Xin Wang, Qinglin Fu, Tianxiao Wu, Yixiang Sun, Nian Liu, Haoyu Zhang, Dongmei Zhao, Maosheng Cheng

By ScienceDirect Publication: European Journal of Medicinal Chemistry, ago

Design, synthesis, and biological evaluation of 4-(2-fluorophenoxy)-7-methoxyquinazoline derivatives as dual EGFR/c-Met inhibitors for the treatment of NSCLC

Publication date: Available online 15 November 2023Source: European Journal of Medicinal ChemistryAuthor(s): Sheng Tang, Chuanchuan Sun, Xintao He, Wenhui Gan, Linxiao Wang, Dan Qiao, Xinyu Guan, Shan Xu, Pengwu Zheng, Wufu Zhu

By ScienceDirect Publication: European Journal of Medicinal Chemistry, ago

Design and synthesis of novel hederagonic acid analogs as potent anti-inflammatory compounds capable of protecting against LPS-induced acute lung injury

Publication date: Available online 14 November 2023Source: European Journal of Medicinal ChemistryAuthor(s): Haixia Li, Wenbin Xie, Xiaojin Gao, Zhiyuan Geng, Jing Gao, Gongshan Ma, Xuanyu Liu, Song Han, Yinchao Chen, Xiaomei Wen, Yi Bi, Leiming Zhang

By ScienceDirect Publication: European Journal of Medicinal Chemistry, ago

A decade of USFDA-approved small molecules as anti-inflammatory agents: Recent trends and Commentaries on the “industrial” perspective

Publication date: Available online 14 November 2023Source: European Journal of Medicinal ChemistryAuthor(s): Vikrant Mehta, Ashish Ranjan Dwivedi, Abhilash Ludhiadch, Vikas Rana, Kapil Kumar Goel, Prerna Uniyal, Gaurav Joshi, Asim Kumar, Bhupinder Kumar

By ScienceDirect Publication: European Journal of Medicinal Chemistry, ago

From garden to lab: C-3 chemical modifications of tomatidine unveil broad-spectrum ATP synthase inhibitors to combat bacterial resistance

Publication date: 15 December 2023Source: European Journal of Medicinal Chemistry, Volume 262Author(s): Julien A. Delbrouck, Alexandre Murza, Iryna Diachenko, Abdelkhalek Ben Jamaa, Runjun Devi, Audrey Larose, Suzanne Chamberland, François Malouin, Pie…

By ScienceDirect Publication: European Journal of Medicinal Chemistry, ago