European Journal of Medicinal Chemistry

A multi-target directed ligands strategy for the treatment of Alzheimer’s disease: Dimethyl fumarate plus Tranilast modified Dithiocarbate as AChE inhibitor and Nrf2 activator

Publication date: 15 November 2022Source: European Journal of Medicinal Chemistry, Volume 242Author(s): Jie Guo, Maojun Cheng, Peng Liu, Duanyuan Cao, Jinchong Luo, Yang Wan, Yuanying Fang, Yi Jin, Sai-Sai Xie, Jing Liu

By ScienceDirect Publication: European Journal of Medicinal Chemistry, ago

Design, synthesis and biological evaluation of (Quinazoline 4-yloxy)acetamide and (4-oxoquinazoline-3(4<em>H</em>)-yl)acetamide derivatives as inhibitors of <em>Mycobacterium tuberculosis bd</em> oxidase

Publication date: 15 November 2022Source: European Journal of Medicinal Chemistry, Volume 242Author(s): Amit Kumar, Neetu Kumari, Sandeep Bhattacherjee, Umamageswaran Venugopal, Shahid Parwez, Mohammad Imran Siddiqi, Manju Y. Krishnan, Gautam Panda

By ScienceDirect Publication: European Journal of Medicinal Chemistry, ago

Synthesis and biological evaluation of novel FiVe1 derivatives as potent and selective agents for the treatment of mesenchymal cancers

Publication date: 15 November 2022Source: European Journal of Medicinal Chemistry, Volume 242Author(s): Francisco Martínez-Peña, Aaron D. Pearson, Eileen L. Tang, Nick A. Kuburich, Sendurai A. Mani, Peter G. Schultz, Michael J. Bollong, Luke L. Lairson

By ScienceDirect Publication: European Journal of Medicinal Chemistry, ago

Discovery of novel PDE4 inhibitors targeting the M-pocket from natural mangostanin with improved safety for the treatment of Inflammatory Bowel Diseases

Publication date: 15 November 2022Source: European Journal of Medicinal Chemistry, Volume 242Author(s): Haobai Liu, Quan Wang, Yue Huang, Jinhui Deng, Xi Xie, Jiaqi Zhu, Yijun Yuan, Yue-Ming He, Yi-You Huang, Hai-Bin Luo, Xixin He

By ScienceDirect Publication: European Journal of Medicinal Chemistry, ago