Design of a structure-activity relationship model of vitamin K epoxide reductase (VKORC1) inhibitors combining chemical synthesis of new compounds, enzymatic assays and molecular modelling

Publication date: Available online 28 August 2023Source: Bioorganic & Medicinal ChemistryAuthor(s): Nolan Chatron, Manon Boulven, Adrien Montagut-Romans, Flavien Ponsot, Maïwenn Jacolot, Hervé Caruel, Etienne Benoît, Florence Popowycz, Virginie Lattard