Bioorganic & Medicinal Chemistry
Junctions in DNA: underexplored targets for therapeutic intervention
Publication date: 1 September 2022Source: Bioorganic & Medicinal Chemistry, Volume 69Author(s): Eleanor Ivens, Marco M.D. Cominetti, Mark Searcey
Bioorganic & Medicinal Chemistry
Fragment hopping protocol for the design of small-molecule protein–protein interaction inhibitors
Publication date: 1 September 2022Source: Bioorganic & Medicinal Chemistry, Volume 69Author(s): Shelby R. Kell, Zhen Wang, Haitao Ji
Bioorganic & Medicinal Chemistry
Bioreducible polyethylenimine core–shell nanostructures as efficient and non-toxic gene and drug delivery vectors
Publication date: 1 September 2022Source: Bioorganic & Medicinal Chemistry, Volume 69Author(s): H. Jena, Z. Ahmadi, P. Kumar, G. Dhawan
Bioorganic & Medicinal Chemistry
pH-responsive Mannose-modified ferrocene Metal-Organic frameworks with rare earth for Tumor-targeted synchronous Chemo/Chemodynamic therapy
Publication date: 1 September 2022Source: Bioorganic & Medicinal Chemistry, Volume 69Author(s): Junliang Dong, Ke Ma, Jindong Ding, Yuxin Pei, Zhichao Pei
Bioorganic & Medicinal Chemistry
Berberine and folic acid co-modified pH-sensitive cascade-targeted PTX-liposomes coated with Tween 80 for treating glioma
Publication date: 1 September 2022Source: Bioorganic & Medicinal Chemistry, Volume 69Author(s): Chunyan Yang, Zhongzhen Yang, Siqi Wang, Jinxia Chen, Qijun Liu, Tianle Huang, Li Hai, Runxin Lu, Yong Wu
Bioorganic & Medicinal Chemistry
Evaluation of crotamine based probes as intracellular targeted contrast agents for magnetic resonance imaging
Publication date: 1 September 2022Source: Bioorganic & Medicinal Chemistry, Volume 69Author(s): Rajendra Joshi, Kamal Sweidan, Deepti Jha, Irina Kerkis, Klaus Scheffler, Joern Engelmann
Bioorganic & Medicinal Chemistry
Entry inhibition of hepatitis B virus using cyclosporin O derivatives with peptoid side chain incorporation
Publication date: 15 August 2022Source: Bioorganic & Medicinal Chemistry, Volume 68Author(s): Dongjae Lee, Jung-Ah Kang, Chanseok Lim, Sunjae Bae, Jieun Choi, Minji Park, Yong-Chul Kim, Yuri Cho, Sung-Gyoo Park, Jiwon Seo
Bioorganic & Medicinal Chemistry
Withaferin A, a polyfunctional pharmacophore that includes covalent engagement of IPO5, is an inhibitor of influenza A replication
Publication date: 1 September 2022Source: Bioorganic & Medicinal Chemistry, Volume 69Author(s): Remi Patouret, Sofia Barluenga, Nicolas Winssinger
Bioorganic & Medicinal Chemistry
Synthesis and biological evaluation of hybrids from optically active ring-opened 3-<em>N</em>-butylphthalide derivatives and 4-fluro-edaravone as potential anti-acute ischemic stroke agents
Publication date: 1 September 2022Source: Bioorganic & Medicinal Chemistry, Volume 69Author(s): Jian Jia, Jianbing Wu, Duorui Ji, Weijie Jiao, Xiaoli Wang, Zhangjian Huang, Yihua Zhang
Bioorganic & Medicinal Chemistry
Design, synthesis, and biological evaluation of a new series of pyrazole derivatives: Discovery of potent and selective JNK3 kinase inhibitors
Publication date: 1 September 2022Source: Bioorganic & Medicinal Chemistry, Volume 69Author(s): Reinad R. Abu Rabah, Anusha Sebastian, Srinivasulu Vunnam, Shaista Sultan, Hamadeh Tarazi, Hanan S. Anbar, Mahmoud K. Shehata, Seyed-Omar Zaraei, Sara M. El…