Bioorganic & Medicinal Chemistry

Structure-Activity Relationship studies on divalent naphthalene diimide G quadruplex ligands with anticancer and antiparasitic activity

Publication date: Available online 26 July 2022Source: Bioorganic & Medicinal ChemistryAuthor(s): Manuel Pérez-Soto, Pablo Peñalver, Steven T. G. Street, Dora Weenink, Michael P. O’Hagan, Javier Ramos, Y. Jennifer Jiang, Gregory J. Hollingworth, M. Car…

By ScienceDirect Publication: Bioorganic & Medicinal Chemistry, ago

Synthesis and biological evaluation of 4-hydroxy-methylpiperidinyl-<em>N</em>-benzyl-acylarylhydrazone hybrids designed as novel multifunctional drug candidates for Alzheimer’s disease

Publication date: 1 October 2022Source: Bioorganic & Medicinal Chemistry, Volume 71Author(s): Sarah Macedo Vaz, Matheus de Freitas Silva, Graziella dos Reis Rosa Franco, Marcos Jorge R. Guimarães, Fernanda Motta R. da Silva, Newton Gonçalves Castro, Is…

By ScienceDirect Publication: Bioorganic & Medicinal Chemistry, ago

<em>In vivo</em> imaging of fluorescent albumin modified with pyruvylated-human-type complex oligosaccharide reveals sialylation-like biodistribution and kinetics

Publication date: Available online 22 July 2022Source: Bioorganic & Medicinal ChemistryAuthor(s): Ryoichiro Fukuhara, Akihiro Ogura, Sho Yoshinaga, Takamasa Fukunaga, Takashi Kinoshita, Wataru Sumiyoshi, Yujiro Higuchi, Katsunori Tanaka, Kaoru Takegawa

By ScienceDirect Publication: Bioorganic & Medicinal Chemistry, ago

Structure-Activity relationship of 1-(Furan-2ylmethyl)Pyrrolidine-Based Stimulation-2 (ST2) inhibitors for treating graft versus host disease

Publication date: Available online 22 July 2022Source: Bioorganic & Medicinal ChemistryAuthor(s): Xinrui Yuan, Hua Jiang, Denggang Fu, Aaron Robida, Krishani Rajanayake, Hebao Yuan, Bo Wen, Duxin Sun, Brennan T. Watch, Krishnapriya Chinnaswamy, Jeanne …

By ScienceDirect Publication: Bioorganic & Medicinal Chemistry, ago