Bioorganic & Medicinal Chemistry
The 2022 Monkeypox outbreak: How the medicinal chemistry could help us?
Publication date: 1 November 2022Source: Bioorganic & Medicinal Chemistry, Volume 73Author(s): Edeildo Ferreira da Silva-Júnior
Bioorganic & Medicinal Chemistry
Structure-activity-relationship study of semi-synthetically modified fusicoccins on their stabilization effect for 14-3-3-phospholigand interactions
Publication date: 1 November 2022Source: Bioorganic & Medicinal Chemistry, Volume 73Author(s): Nanami Ogino, Ryoma Masuda, Louvy Lynn Punzalan, Emi Yamashita, Shota Igaue, Yoshihisa Inoue, Junko Ohkanda
Bioorganic & Medicinal Chemistry
Design and evaluation of novel analogs of 2-amino-4-boronobutanoic acid (ABBA) as inhibitors of human gamma-glutamyl transpeptidase
Publication date: 1 November 2022Source: Bioorganic & Medicinal Chemistry, Volume 73Author(s): Luong Nguyen, Daniel C. Schultz, Simon S. Terzyan, Mohammad Rezaei, Jinhua Songb, Chenglong Li, Youngjae You, Marie H. Hanigan
Bioorganic & Medicinal Chemistry
Identification of PI3K/HDAC Dual-targeted inhibitors with subtype selectivity as potential therapeutic agents against solid Tumors: Building HDAC6 potency in a Quinazolinone-based PI3Kδ-selective template
Publication date: 1 November 2022Source: Bioorganic & Medicinal Chemistry, Volume 73Author(s): Zhi Li, Can Zhao, Ge He, Yujie Wang, Yang Wang, Xiaodong Ma
Bioorganic & Medicinal Chemistry
Dual MVK cleavable linkers effectively reduce renal retention of <sup>111</sup>In-fibronectin-binding peptides
Publication date: 1 November 2022Source: Bioorganic & Medicinal Chemistry, Volume 73Author(s): Giulia Valpreda, Belinda Trachsel, Viola Vogel, Roger Schibli, Linjing Mu, Martin Behe
Bioorganic & Medicinal Chemistry
Improving lipophilicity of 5-(1-acetyl-5-phenylpyrazolidin-3-ylidene)-1,3-dimethylbarbituric acid increases its efficacy to activate hypoxia-inducible factors
Publication date: 1 November 2022Source: Bioorganic & Medicinal Chemistry, Volume 73Author(s): Kento Sonoda, Saki Ujike, Akito Katayama, Norio Suzuki, Shin-ichi Kawaguchi, Tadayuki Tsujita
Bioorganic & Medicinal Chemistry
A concise synthesis of <span class=”small-caps”>l</span>-gulose and its C-6 derivatives
Publication date: 1 November 2022Source: Bioorganic & Medicinal Chemistry, Volume 73Author(s): Kai-Ching Teng, Kuei-Yao Tseng, Zheng-Hao Tzeng, Shang-Cheng Hung
Bioorganic & Medicinal Chemistry
Evaluation of acute toxicity of cancer-targeting albumin-based artificial metalloenzymes
Publication date: 1 November 2022Source: Bioorganic & Medicinal Chemistry, Volume 73Author(s): Tsung-Che Chang, Igor Nasibullin, Kyohei Muguruma, Yuriko Kusakari, Taiji Shimoda, Katsunori Tanaka
Bioorganic & Medicinal Chemistry
Discovery and optimization of orally bioavailable and potent plasma Kallikrein inhibitors bearing a quaternary carbon
Publication date: 1 November 2022Source: Bioorganic & Medicinal Chemistry, Volume 73Author(s): Weihe Zhang, Satish Vadlakonda, Minwan Wu, Venkat Chintareddy, LN Vogeti, Luis Juarez, Saritha Muppa, Cynthia Parker, Debra Kellogg-Yelder, Jason Williams, K…
Bioorganic & Medicinal Chemistry
Nucleic acid extraction from complex biofluid using toothpick-actuated over-the-counter medical-grade cotton
Publication date: 1 November 2022Source: Bioorganic & Medicinal Chemistry, Volume 73Author(s): Shrawan Kumar, Anjali Kharb, Aman Vazirani, Rajinder Singh Chauhan, Goutam Pramanik, Mrittika Sengupta, Souradyuti Ghosh