Discovery of Novel Dual Bruton’s Tyrosine Kinase (BTK) and Janus Kinase 3 (JAK3) Inhibitors as A Promising Strategy for Rheumatoid Arthritis

Publication date: Available online 27 May 2023Source: Bioorganic & Medicinal ChemistryAuthor(s): Tingting Liang, Lifang Cen, Junjie Wang, Ming Cheng, Weibo Guo, Wenjie Wang, Chunqiu Yu, Haifeng Zhang, Yuan Wang, Zhongyan Hao, Jiaming Jin, Yaoyao Wu, Te…

Novel drug-like fluorenyl derivatives as selective butyrylcholinesterase and β-amyloid inhibitors for the treatment of Alzheimer’s disease

Publication date: Available online 18 May 2023Source: Bioorganic & Medicinal ChemistryAuthor(s): Anna Pasieka, Dawid Panek, Paula Zaręba, Emilia Sługocka, Natalia Gucwa, Alba Espargaró, Gniewomir Latacz, Nadia Khan, Adam Bucki, Raimon Sabaté, Anna Więc…