Optimization of clofibrate with O-desmethyl anetholtrithione lead to a novel hypolipidemia compound with hepatoprotective effect

Publication date: 15 September 2022Source: Bioorganic & Medicinal Chemistry Letters, Volume 72Author(s): Haitao Liu, Panpan Zhang, Xiaoxiao Ge, Qiong Wu, Chuchu Han, Linyang Zhang, Yuxin Hua, Yuxuan Zhang, Jiping Liu, Yongheng Shi, Bin Wang, Xiaoping W…

Identification and <em>in vitro</em> characterization of a new series of potent and highly selective G9a inhibitors as novel anti-fibroadipogenic agents

Publication date: 15 September 2022Source: Bioorganic & Medicinal Chemistry Letters, Volume 72Author(s): Pietro Randazzo, Roberta Sinisi, Davide Gornati, Stefania Bertuolo, Leda Bencheva, Marilenia De Matteo, Martina Nibbio, Edith Monteagudo, Lorenzo T…