Bioorganic & Medicinal Chemistry Letters
Synthesis of a tricyclic hexapeptide –via two consecutive ruthenium-catalyzed macrocyclization steps– with a constrained topology to mimic vancomycin’s binding properties toward D-Ala-D-Ala dipeptide
Publication date: Available online 11 July 2022Source: Bioorganic & Medicinal Chemistry LettersAuthor(s): Xin Yang, Johan Kemmink, Dirk T.S. Rijkers, Rob M.J. Liskamp