Bioorganic & Medicinal Chemistry Letters

Identification of a new and diverse set of <em>Mycobacterium tuberculosis</em> uracil-DNA glycosylase (<em>Mt</em>Ung) inhibitors using structure-based virtual screening: Experimental validation and molecular dynamics studies

Publication date: 15 November 2022Source: Bioorganic & Medicinal Chemistry Letters, Volume 76Author(s): Prateek Raj, Karthik Selvam, Koyel Roy, Shailesh Mani Tripathi, Sharyu Kesharwani, Balasubramanian Gopal, Umesh Varshney, Sandeep Sundriyal

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Guanidino Quinazolines and Pyrimidines Promote Readthrough of Premature Termination Codons in Cells with Native Nonsense Mutations

Publication date: Available online 20 September 2022Source: Bioorganic & Medicinal Chemistry LettersAuthor(s): Morrill Christie, J. Friesen Westley, Babu Suresh, Y. Baiazitov Ramil, Du Wu, B. Karloff Diane, Lee Chang-Sun, Moon Young-Choon, Ren Hongyu, …

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Structure-based design and modular synthesis of novel PI4K class II inhibitors bearing a 4-aminoquinazoline scaffold

Publication date: Available online 29 September 2022Source: Bioorganic & Medicinal Chemistry LettersAuthor(s): Mbilo Misehe, Martin Klima, Marika Matoušová, Dominika Chalupská, Milan Dejmek, Michal Šála, Helena Mertlíková-Kaiserová, Evzen Boura, Radim …

By ScienceDirect Publication: Bioorganic & Medicinal Chemistry Letters, ago