Bioorganic & Medicinal Chemistry

Design, synthesis, and biological evaluation of quinazoline–benzohydrazide and quinazoline–benzothiazole hybrids uncovering a dual EGFR/VEGFR-2 inhibitor with pronounced cytotoxic activity against triple-negative breast Cancer

Publication date: Available online 6 December 2025Source: Bioorganic & Medicinal ChemistryAuthor(s): Noura F.M. El Hamaky, Abdelrahman Hamdi, Waleed A. Bayoumi, Abdullah A. Elgazar, Magda N.A. Nasr

By ScienceDirect Publication: Bioorganic & Medicinal Chemistry, ago

Design, synthesis, and biological evaluation of a focused pyrrolo- and pyrido-quinazolinone natural products-templated library for anti-fungal and anthelmintic activities

Publication date: Available online 5 December 2025Source: Bioorganic & Medicinal ChemistryAuthor(s): Romina E. D’Almeida, Paulina Chen, Yanchang Huang, Emily Goetz, Vamshikrishna Reddy Sammeta, Bo Yang, Reeta Rao, Sivappa Rasapalli, Mostafa Elfawal

By ScienceDirect Publication: Bioorganic & Medicinal Chemistry, ago