ChemistrySelect
Microwave Synthesized Hydrophilic 4‐Oxo‐2‐phenylquinazoline‐3(4H)–carboximidamide and –Carboxamide as Privileged Small Molecule Scaffolds with Anti‐HIV‐1 Activities
ChemistrySelect, Volume 8, Issue 37, October 6, 2023.
ChemistrySelect, Volume 8, Issue 37, October 6, 2023.
ChemistrySelect, Volume 8, Issue 37, October 6, 2023.
ChemistrySelect, Volume 8, Issue 37, October 6, 2023.
ChemistrySelect, Volume 8, Issue 37, October 6, 2023.
ChemistrySelect, Volume 8, Issue 37, October 6, 2023.
ChemistrySelect, Volume 8, Issue 37, October 6, 2023.
ChemistrySelect, Volume 8, Issue 37, October 6, 2023.
Volume 199, Issue 1, 2024, Page 90-102.
Volume 43, Issue 6, 2023, Page 320-336.
An alkoxylation of N,N-dialkyl amides by the Shono reaction has been developed that offers a simple and efficient way to access N-adjacent-carbon-substituted amides. TMSN3 plays an essential role in this transformation and permits the reaction to proceed with a broad substrate scope under mild conditions. This reaction proceeds at a lower current compared with the classical method and it affords the products in up to 91% yield. A possible mechanism is proposed based on control experiments.