Identification of pyrrolo[3′,4’:3,4]cyclohepta[1,2-<em>d</em>][1,2]oxazoles as promising new candidates for the treatment of lymphomas

Publication date: 5 June 2023Source: European Journal of Medicinal Chemistry, Volume 254Author(s): Marilia Barreca, Virginia Spanò, Roberta Rocca, Roberta Bivacqua, Gianmarco Gualtieri, Maria Valeria Raimondi, Eugenio Gaudio, Roberta Bortolozzi, Lorenz…

Design, synthesis and biological evaluation of pyrrolopyrimidine derivatives as novel and selective positive modulator of the small conductance Ca<sup>2+</sup>-activated K<sup>+</sup> channels

Publication date: 5 June 2023Source: European Journal of Medicinal Chemistry, Volume 254Author(s): Ran Guo, Miao Cui, Xiaojing Li, Mengqi Wu, Fei Xu, Yining Zhang, Chun Wang, Penglei Feng, Jianchao Wang, Sijia Huo, Zijun Luo, Ruijuan Xing, Jianmin Gu, …

Discovery of a spirocyclic 3-bromo-4,5-dihydroisoxazole covalent inhibitor of hGAPDH with antiproliferative activity against pancreatic cancer cells

Publication date: 5 June 2023Source: European Journal of Medicinal Chemistry, Volume 254Author(s): Andrea Galbiati, Stefania Bova, Raffaella Pacchiana, Chiara Borsari, Marco Persico, Aureliano Zana, Stefano Bruno, Massimo Donadelli, Caterina Fattorusso…

Corrigendum to “Discovery of a potent, selective and cell active inhibitor of m6A demethylase ALKBH5” [Eur. J. Med. Chem. 238 (2022) 114446]

Publication date: 5 July 2023Source: European Journal of Medicinal Chemistry, Volume 255Author(s): Zhen Fang, Bo Mu, Yang Liu, Nihong Guo, Liang Xiong, Yinping Guo, Anjie Xia, Rong Zhang, Hailin Zhang, Rui Yao, Yan Fan, Linli Li, Shengyong Yang, Rong X…