Multicomponent Petasis reaction for the identification of pyrazine based multi-target directed anti-Alzheimer’s agents: <em>In-silico</em> design, synthesis, and characterization

Publication date: 5 June 2023Source: European Journal of Medicinal Chemistry, Volume 254Author(s): Hari Madhav, Somaya A. Abdel-Rahman, Md Amiruddin Hashmi, Md Ataur Rahman, Mohammad Rehan, Kavita Pal, Shahid M. Nayeem, Moustafa T. Gabr, Nasimul Hoda

Design, synthesis and evaluation of novel pyrrole-hydroxybutenolide hybrids as promising antiplasmodial and anti-inflammatory agents

Publication date: 5 June 2023Source: European Journal of Medicinal Chemistry, Volume 254Author(s): Alka Raj Pandey, Suriya Pratap Singh, Prince Joshi, Kunwar Satyadeep Srivastav, Smriti Srivastava, Kanchan Yadav, Ramesh Chandra, Amol Chhatrapati Bisen,…

Design and synthesis of fascaplysin derivatives as inhibitors of FtsZ with potent antibacterial activity and mechanistic study

Publication date: 5 June 2023Source: European Journal of Medicinal Chemistry, Volume 254Author(s): Hongda Qiu, Xing Zhao, Yinli Jiang, Weida Liang, Weile Wang, Xingyao Jiang, Mengying Jiang, Xiao Wang, Wei Cui, Yang Li, Keqi Tang, Tao Zhang, Lingling Z…