May 2023

Anti-inflammatory efficacy and relevant SAR investigations of novel chiral pyrazolo isoquinoline derivatives: Design, synthesis, in-vitro, in-vivo, and computational studies targeting iNOS

Publication date: Available online 28 April 2023Source: European Journal of Medicinal ChemistryAuthor(s): Maryam Akhtar, Jiabin Niu, Yujie Zhu, Zhaoyi Luo, Ting Tian, Yuanliang Dong, Yuan Wang, Muhammad Subaan Fareed, Li Lin

By ScienceDirect Publication: European Journal of Medicinal Chemistry, ago

Scaffold hopping of <em>N</em>-benzyl-3,4,5-trimethoxyaniline: 5,6,7-Trimethoxyflavan derivatives as novel potential anticancer agents modulating hippo signaling pathway

Publication date: Available online 26 April 2023Source: European Journal of Medicinal ChemistryAuthor(s): Ahmed H.E. Hassan, Cai Yi Wang, Hyo Jong Lee, Su Jin Jung, Yeon Ju Kim, Soo Bin Cho, Chae Hyeon Lee, Gyeongpyo Ham, Taegeun Oh, Sang Kook Lee, Yon…

By ScienceDirect Publication: European Journal of Medicinal Chemistry, ago

Exploration of imatinib and nilotinib-derived templates as the P2-Ligand for HIV-1 protease inhibitors: Design, synthesis, protein X-ray structural studies, and biological evaluation

Publication date: Available online 21 April 2023Source: European Journal of Medicinal ChemistryAuthor(s): Arun K. Ghosh, Jennifer L. Mishevich, Satish Kovela, Ryan Shaktah, Ajay K. Ghosh, Megan Johnson, Yuan-Fang Wang, Andres Wong-Sam, Johnson Agniswam…

By ScienceDirect Publication: European Journal of Medicinal Chemistry, ago