Discovery of novel, potent, and orally bioavailable HDACs inhibitors with LSD1 inhibitory activity for the treatment of solid tumors

Publication date: 5 June 2023Source: European Journal of Medicinal Chemistry, Volume 254Author(s): Yingchao Duan, Tong Yu, Linfeng Jin, Shaojie Zhang, Xiaojing Shi, Yizhe Zhang, Nanqian Zhou, Yongtao Xu, Wenfeng Lu, Huimin Zhou, Huijuan Zhu, Suping Bai…

Biological activity of 1,2,3-triazole-2-amino-1,4-naphthoquinone derivatives and their evaluation as therapeutic strategy for malaria control

Publication date: 5 July 2023Source: European Journal of Medicinal Chemistry, Volume 255Author(s): Renata Maria Costa Souza, Lilian Maria Lapa Montenegro Pimentel, Laryssa Kathleen Mendonça Ferreira, Valéria Rêgo Alves Pereira, Aline Caroline Da Silva …