March 2023

Designed multiple ligands for the treatment of type 2 diabetes mellitus and its complications: Discovery of (5-arylidene-4-oxo-2-thioxothiazolidin-3-yl)alkanoic acids active as novel dual-targeted PTP1B/AKR1B1 inhibitors

Publication date: 5 April 2023Source: European Journal of Medicinal Chemistry, Volume 252Author(s): Rosanna Maccari, Gerhard Wolber, Massimo Genovese, Gemma Sardelli, Valerij Talagayev, Francesco Balestri, Simone Luti, Alice Santi, Roberta Moschini, An…

By ScienceDirect Publication: European Journal of Medicinal Chemistry, ago

Discovery of novel <em>N</em>-benzylarylamide-dithiocarbamate based derivatives as dual inhibitors of tubulin polymerization and LSD1 that inhibit gastric cancers

Publication date: 5 April 2023Source: European Journal of Medicinal Chemistry, Volume 252Author(s): Xin-Ying Yuan, Chun-Hong Song, Xiu-Juan Liu, Xiao Wang, Mei-Qi Jia, Wang Wang, Wen-Bo Liu, Xiang-Jing Fu, Cheng-Yun Jin, Jian Song, Sai-Yang Zhang

By ScienceDirect Publication: European Journal of Medicinal Chemistry, ago