Nature Biotechnology, Published online: 07 October 2024; doi:10.1038/s41587-024-02404-ySample, financial and labor requirements are key barriers to scaling up high-content phenotypic discovery efforts. A broadly applicable method overc…
Nature Biotechnology, Published online: 07 October 2024; doi:10.1038/s41587-024-02456-0Publisher Correction: Multistate and functional protein design using RoseTTAFold sequence space diffusion
Nature Biotechnology, Published online: 07 October 2024; doi:10.1038/s41587-024-02454-2Author Correction: Efficient genetic code expansion without host genome modifications
Nature Biotechnology, Published online: 07 October 2024; doi:10.1038/s41587-024-02426-6SCOPE detects low-abundance extracellular vesicle mRNA with high sensitivity for clinical applications.
Nature Biotechnology, Published online: 07 October 2024; doi:10.1038/s41587-024-02391-0Optical pooled screening is enhanced by amplification of barcodes before in situ sequencing.
Nature Biotechnology, Published online: 07 October 2024; doi:10.1038/s41587-024-02386-xOptical pooled CRISPR screening is improved by combinatorial oligo hybridization for barcode detection.
Nature Biotechnology, Published online: 07 October 2024; doi:10.1038/s41587-024-02403-zPhenotypic screens in organoids and primary cells are scaled up using perturbation pooling.
Nature Biotechnology, Published online: 07 October 2024; doi:10.1038/s41587-024-02455-1The time has come for biotech companies to embrace machine learning for clinical trials, but they should start with compiling the data. That means g…
Nature Biotechnology, Published online: 07 October 2024; doi:10.1038/s41587-024-02440-8A CRISPR-based assay both recognizes and amplifies target mRNA, achieving sub-attomolar sensitivity with single-nucleotide resolution. This method e…
Nature Biotechnology, Published online: 07 October 2024; doi:10.1038/s41587-024-02434-6Two major advances in optical pooled screening improve substantially on sensitivity and robustness, expanding its applicability to a broader range o…