Nature Biotechnology
The rise of patient avatars in precision oncology
Nature Biotechnology, Published online: 26 July 2024; doi:10.1038/s41587-024-02335-8The rise of patient avatars in precision oncology
Nature Biotechnology
A mini-colon models colon cancer and its microenvironment
Nature Biotechnology, Published online: 25 July 2024; doi:10.1038/s41587-024-02343-8A mini-colon device mimics colorectal tumors and their interactions with neighboring healthy tissue, stromal cells and immune cells.
Nature Biotechnology
Author Correction: Quantifying bias introduced by sample collection in relative and absolute microbiome measurements
Nature Biotechnology, Published online: 24 July 2024; doi:10.1038/s41587-024-02341-wAuthor Correction: Quantifying bias introduced by sample collection in relative and absolute microbiome measurements
Nature Biotechnology
Large-scale discovery of chromatin dysregulation induced by oncofusions and other protein-coding variants
Nature Biotechnology, Published online: 24 July 2024; doi:10.1038/s41587-024-02347-4The effects of oncofusions and other protein variants on chromatin remodeling are identified by PROD-ATAC.
Nature Biotechnology
Click editing enables programmable genome writing using DNA polymerases and HUH endonucleases
Nature Biotechnology, Published online: 22 July 2024; doi:10.1038/s41587-024-02324-xClick editing uses DNA polymerases, HUH endonucleases and oligonucleotide templates for genome modification.
Nature Biotechnology
Editor’s pick: Indapta Therapeutics
Nature Biotechnology, Published online: 22 July 2024; doi:10.1038/s41587-024-02334-9Each year, Nature Biotechnology highlights companies that have received sizeable early-stage funding in the previous year. Indapta Therapeutics is usin…
Nature Biotechnology
Precise and versatile genome editing with click editors
Nature Biotechnology, Published online: 22 July 2024; doi:10.1038/s41587-024-02340-xWe developed click editors, comprising HUH endonucleases, DNA-dependent DNA polymerases and CRISPR–Cas9 nickases, which together enable programmable pr…
Nature Biotechnology
Cryo-EM structure of a prime editor complex in multiple states
Nature Biotechnology, Published online: 17 July 2024; doi:10.1038/s41587-024-02325-wCryo-EM structure of a prime editor complex in multiple states
Nature Biotechnology
Forum: Lancaster and Pașca
Nature Biotechnology, Published online: 17 July 2024; doi:10.1038/s41587-024-02331-yForum: Lancaster and Pașca
Nature Biotechnology
Counteracting tissue aging through TERT activation
Nature Biotechnology, Published online: 17 July 2024; doi:10.1038/s41587-024-02327-8Counteracting tissue aging through TERT activation