Nature Biotechnology, Published online: 06 November 2024; doi:10.1038/s41587-024-02478-8Europe’s first field trial of gene-edited vines began in northern Italy on 30 September 2024. Developed by EdiVite, a spinoff from the University o…
Nature Biotechnology, Published online: 05 November 2024; doi:10.1038/s41587-024-02468-wAncestral sequence reconstruction enables the identification and synthesis of ReChb, an ancient form of CRISPR–Cas12a with a highly versatile funct…
Nature Biotechnology, Published online: 04 November 2024; doi:10.1038/s41587-024-02472-0A strategic move by lawyers acting for Doudna and Charpentier is the latest twist in the battleground for CRISPR–Cas9 technology.
Nature Biotechnology, Published online: 04 November 2024; doi:10.1038/s41587-024-02462-2Agrobacterium-mediated transformation of plants and fungi is enhanced by plasmid copy number variants.
Nature Biotechnology, Published online: 04 November 2024; doi:10.1038/s41587-024-02469-9AIntibody: an experimentally validated in silico antibody discovery design challenge
Nature Biotechnology, Published online: 04 November 2024; doi:10.1038/s41587-024-02480-0The Nobel Prize in medicine was awarded for the discovery of miRNA, but miRNA therapeutics have a long way to go before they outcompete other thera…
Nature Biotechnology, Published online: 04 November 2024; doi:10.1038/s41587-024-02460-4Peroxides localized at oxidative stress sites trigger prodrug release for treating chronic pain in mice.
Nature Biotechnology, Published online: 01 November 2024; doi:10.1038/s41587-024-02442-6Improved effectors for CRISPRi/CRISPRa are developed following high-throughput screening of transcriptional domains.
Nature Biotechnology, Published online: 31 October 2024; doi:10.1038/s41587-024-02461-3ReChb is a Cas12a nuclease with expanded target access and substrate recognition.
Nature Biotechnology, Published online: 25 October 2024; doi:10.1038/s41587-024-02382-1DRAGEN rapidly identifies diverse types of genetic variants.