Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. High-throughput transcriptomics has advanced through the introduction of TempO-seq, a targeted alternative to traditional RNA-seq. TempO-seq platforms use 50 nucleotide prob…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. The serine incorporator (SERINC) family of proteins are a family of multipass transmembrane proteins associated with biosynthesis of serine-containing phospholipids and sphi…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. Rhodobacter capsulatus is a purple non-sulfur bacteria widely used as a model organism to study bacterial photosynthesis. It exhibits extensive metabolic activities and demo…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. This work explores how much the traditional approach to modeling and simulation of biological systems, specifically cell signaling networks, can be increased and improved by…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. Drug discovery (DD) research is a complex field with a high attrition rate. Machine learning (ML) approaches combined to chemoinformatics are of valuable input to this field…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. Background:Rheumatoid arthritis (RA) is an autoimmune disease characterised by systemic inflammation of joints. The observed complexity of RA pathogenesis and studies that h…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. Cancer is a major health problem worldwide and the leading cause of death in many countries. It remains challenging to find anticancer treatments that work efficiently for v…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. Differential expressions of certain genes during tumorigenesis may serve to identify novel manageable targets in the clinic. In this work with an integrated bioinformatics a…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. We previously developed a method of defining receptor clusters in the membrane based on mutual distance and applied it to a set of transmission microscopy images of vascular…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. As SARS-CoV-2 continues to evolve and spread with the emergence of new variants, interest in small molecules with broad-spectrum antiviral activity has grown. One such molec…