Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. Drug discovery (DD) research is a complex field with a high attrition rate. Machine learning (ML) approaches combined to chemoinformatics are of valuable input to this field…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. Background:Rheumatoid arthritis (RA) is an autoimmune disease characterised by systemic inflammation of joints. The observed complexity of RA pathogenesis and studies that h…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. Cancer is a major health problem worldwide and the leading cause of death in many countries. It remains challenging to find anticancer treatments that work efficiently for v…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. Differential expressions of certain genes during tumorigenesis may serve to identify novel manageable targets in the clinic. In this work with an integrated bioinformatics a…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. We previously developed a method of defining receptor clusters in the membrane based on mutual distance and applied it to a set of transmission microscopy images of vascular…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. As SARS-CoV-2 continues to evolve and spread with the emergence of new variants, interest in small molecules with broad-spectrum antiviral activity has grown. One such molec…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. Fundamental principles of HIV-1 integration into the human genome have been revealed in the past 2 decades. However, the impact of the integration site on proviral transcrip…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. Background:Coronavirus disease 2019 (COVID-19), caused by novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a global epidemic with a high mortality rate…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. With the advent of next-generation whole-genome sequencing (WGS), the need for good-quality and well-characterised Salmonella genomes has increased over the past years. Good…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. Parkinson’s disease (PD) is a neurodegenerative disorder responsible for shaking, rigidity, and trouble in walking and patients’ coordination ability and physical stability …