Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. Multiple sclerosis (MS) is a central nervous disorder caused by several factors. Studies have recently shown that non-coding RNA such as miRNA could participate in MS initia…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. β-thalassemia is a significant health issue worldwide, with approximately 7% of the world’s population having defective hemoglobin genes. MicroRNAs (miRNAs) are short noncod…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. There are many copy number variation (CNV) detection tools based on the depth of coverage. A characteristic feature of all tools based on the depth of coverage is the first …
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. The sodium-dependent serotonin transporter SLC6A4 (solute carrier family 6 member 4) gene encodes an intrinsic membrane protein that transmits the serotonin neurotransmitter…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. Schistosomiasis, a disease usually related to poverty and poor sanitation, affects more than 200 million people worldwide. Since the 1970s, the medical sector has depended o…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. Epitopes are portions of a protein that are recognized by antibodies. These small amino acid sequences represent a significant breakthrough in a branch of bioinformatics cal…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. High-throughput transcriptomics has advanced through the introduction of TempO-seq, a targeted alternative to traditional RNA-seq. TempO-seq platforms use 50 nucleotide prob…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. The serine incorporator (SERINC) family of proteins are a family of multipass transmembrane proteins associated with biosynthesis of serine-containing phospholipids and sphi…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. Rhodobacter capsulatus is a purple non-sulfur bacteria widely used as a model organism to study bacterial photosynthesis. It exhibits extensive metabolic activities and demo…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. This work explores how much the traditional approach to modeling and simulation of biological systems, specifically cell signaling networks, can be increased and improved by…