Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. Most recently, monkeypox virus (MPXV) has emanated as a global public health threat. Unavailability of effective medicament against MPXV escalates demand for new therapeutic…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. MicroRNAs are small non-coding RNA molecules that are produced in a cell endogenously. They are made up of 18 to 26 nucleotides in strength. Due to their evolutionary conser…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. Previously, we showed that novel histone deacetylase (HDAC) inhibitors, N1-hydroxy-N8-(4-(pyridine-2-carbothioamido)phenyl)octanediamide (Jazz90) and [chlorido(η5-pentamethy…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. The “Severe Acute Respiratory Syndrome” (SARS), which has relation to the coronavirus-2 considered to be a major cause of the disease addressed by COVID-19. COVID-19 require…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. Dengue and Japanese encephalitis virus (JEV) are mosquito-borne RNA viruses that can cause severe illness leading to death in the tropics and subtropics. Both of these virus…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. Ovarian clear cell carcinoma (OCCC), one of the histopathological types of ovarian cancer, has a poor prognosis when it recurs; however, it is difficult to precisely predict…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. Vibrio parahaemolyticus, an aquatic pathogen, is a major concern in the shrimp aquaculture industry. Several strains of this pathogen are responsible for causing acute hepat…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. The human immunodeficiency virus (HIV) infection and the associated acquired immune deficiency syndrome (AIDS) remain global challenges even after decades of successful trea…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. Hemophilia is an inherited blood coagulation disorder caused by mutations on the coagulation factors VIII or IX genes. Although it is a relatively rare disease, the research…
Bioinformatics and Biology Insights, Volume 16, Issue , January-December 2022. Whole genome sequencing has rapidly progressed in recent years, with sequencing the SARS-CoV-2 genomes, making it a more reliable clinical tool for public health surveillanc…