Bioorganic Chemistry

HDAC1/MAO-B dual inhibitors against Alzheimer’s disease: Design, synthesis and biological evaluation of N-propargylamine-hydroxamic acid/o-aminobenzamide hybrids

Publication date: May 2022Source: Bioorganic Chemistry, Volume 122Author(s): Chuansheng Yao, Xiaoying Jiang, Rui Zhao, Zhichao Zhong, Jiamin Ge, Junlong Zhu, Xiang-Yang Ye, Yuanyuan Xie, Zhen Liu, Tian Xie, Renren Bai

By ScienceDirect Publication: Bioorganic Chemistry, 3 years ago

Bioorganic Chemistry

Escherichia coli tRNA 2-selenouridine synthase SelU selects its prenyl substrate to accomplish its enzymatic function

Publication date: May 2022Source: Bioorganic Chemistry, Volume 122Author(s): Patrycja Szczupak, Ewa Radzikowska-Cieciura, Katarzyna Kulik, Rafał Madaj, Małgorzata Sierant, Agnieszka Krakowiak, Barbara Nawrot

By ScienceDirect Publication: Bioorganic Chemistry, 3 years ago

Bioorganic Chemistry

Identification and molecular mechanism of a tri-peptide inhibitor targeting iNOS from duck embryo protein hydrolysates by experimental and bioinformatics studies

Publication date: May 2022Source: Bioorganic Chemistry, Volume 122Author(s): Yudi Peng, Lijun Bu, Xiaochun Zhang, Zhengmei Ji, Huadong Xie, Guizhao Liang

By ScienceDirect Publication: Bioorganic Chemistry, 3 years ago

Bioorganic Chemistry

Novel third-generation pyrimidines-based EGFR tyrosine kinase inhibitors targeting EGFR T790M mutation in advanced non-small cell lung cancer

Publication date: May 2022Source: Bioorganic Chemistry, Volume 122Author(s): Baijiao An, Jian Liu, Yangyang Fan, Wenyan Nie, Chunhua Yang, Han Yao, Wei Li, Yin Zhang, Xingshu Li, Geng Tian

By ScienceDirect Publication: Bioorganic Chemistry, 3 years ago

Bioorganic Chemistry

Synthesis, antiviral and antitumor activities investigations of a series of Ribavirin C-nucleoside analogue prodrugs

Publication date: May 2022Source: Bioorganic Chemistry, Volume 122Author(s): Nazarii Sabat, Abdelhakim Ouarti, Evelyne Migianu-Griffoni, Marc Lecouvey, Olivier Ferraris, Florian Gallier, Christophe Peyrefitte, Nadège Lubin-Germain, Jacques Uziel

By ScienceDirect Publication: Bioorganic Chemistry, 3 years ago

Bioorganic Chemistry

Development of a cysteine responsive chlorinated hemicyanine for image-guided dual phototherapy

Publication date: May 2022Source: Bioorganic Chemistry, Volume 122Author(s): Samira Savani, Kubra Onbasli, Hande Gunduz, Eda Aydındogan, Merve Erkısa, Abdullah Muti, Minahil Khan, Alphan Sennaroglu, Engin Ulukaya, Havva Yagci Acar, Safacan Kolemen

By ScienceDirect Publication: Bioorganic Chemistry, 3 years ago

Bioorganic Chemistry

Targeting the HVEM protein using a fragment of glycoprotein D to inhibit formation of the BTLA/HVEM complex

Publication date: May 2022Source: Bioorganic Chemistry, Volume 122Author(s): Katarzyna Kuncewicz, Claire Battin, Katarzyna Węgrzyn, Adam Sieradzan, Anna Wardowska, Emilia Sikorska, Irma Giedrojć, Pamela Smardz, Michał Pikuła, Peter Steinberger, Sylwia …

By ScienceDirect Publication: Bioorganic Chemistry, 3 years ago

Bioorganic Chemistry

A new isothiocyanate-based Golgi-targeting fluorescent probe for Cys and its bioimaging applications during the Golgi stress response

Publication date: May 2022Source: Bioorganic Chemistry, Volume 122Author(s): Hanchuang Zhu, Caiyun Liu, Xiaodi Rong, Yan Zhang, Meijun Su, Xin Wang, Mengyuan Liu, Xiaohui Zhang, Wenlong Sheng, Baocun Zhu

By ScienceDirect Publication: Bioorganic Chemistry, 3 years ago

Bioorganic Chemistry

Dihydroartemisinin alleviates steatosis and inflammation in nonalcoholic steatohepatitis by decreasing endoplasmic reticulum stress and oxidative stress

Publication date: May 2022Source: Bioorganic Chemistry, Volume 122Author(s): Tongxi Li, Yifan Chen, Peng Tan, Hao Shi, Zhiwei Huang, Tianying Cai, Yonglang Cheng, Yichao Du, Wenguang Fu

By ScienceDirect Publication: Bioorganic Chemistry, 3 years ago

Bioorganic Chemistry

Design and synthesis of Aza-boeravinone derivatives as potential novel topoisomerase I inhibitors

Publication date: May 2022Source: Bioorganic Chemistry, Volume 122Author(s): Yong Zhou, Yin-Peng Bai, Mi Zhang, Jian-Mei Gao, Cheng-Jie Yang, Zhi-Jun Zhang, Nan Deng, Lei Li, Ying-Qian Liu, Chuan-Rui Xu

By ScienceDirect Publication: Bioorganic Chemistry, 3 years ago

Bioorganic Chemistry

Bioorganic Chemistry

HDAC1/MAO-B dual inhibitors against Alzheimer’s disease: Design, synthesis and biological evaluation of <em>N</em>-propargylamine-hydroxamic acid/<em>o</em>-aminobenzamide hybrids

Bioorganic Chemistry

<em>Escherichia coli</em> tRNA 2-selenouridine synthase SelU selects its prenyl substrate to accomplish its enzymatic function

Bioorganic Chemistry

Identification and molecular mechanism of a tri-peptide inhibitor targeting iNOS from duck embryo protein hydrolysates by experimental and bioinformatics studies

Bioorganic Chemistry

Novel third-generation pyrimidines-based EGFR tyrosine kinase inhibitors targeting EGFR T790M mutation in advanced non-small cell lung cancer

Bioorganic Chemistry

Synthesis, antiviral and antitumor activities investigations of a series of Ribavirin <em>C</em>-nucleoside analogue prodrugs

Bioorganic Chemistry

Development of a cysteine responsive chlorinated hemicyanine for image-guided dual phototherapy

Bioorganic Chemistry

Targeting the HVEM protein using a fragment of glycoprotein D to inhibit formation of the BTLA/HVEM complex

Bioorganic Chemistry

A new isothiocyanate-based Golgi-targeting fluorescent probe for Cys and its bioimaging applications during the Golgi stress response

Bioorganic Chemistry

Dihydroartemisinin alleviates steatosis and inflammation in nonalcoholic steatohepatitis by decreasing endoplasmic reticulum stress and oxidative stress

Bioorganic Chemistry

Design and synthesis of Aza-boeravinone derivatives as potential novel topoisomerase I inhibitors