Nature Chemical Biology, Published online: 21 March 2022; doi:10.1038/s41589-022-00985-wThe use of NMR spectroscopy and development of a cellular BRET KRAS engagement assay revealed that noncovalent ligands can access the switch-II poc…
Nature Chemical Biology, Published online: 21 March 2022; doi:10.1038/s41589-022-01000-yDespite well-established tumorigenic roles of KRAS mutants, targeting their smooth surfaces was a challenge, which was overcome through the develop…
Nature Chemical Biology, Published online: 17 March 2022; doi:10.1038/s41589-022-00998-5Natural self-cleaving RNAs employ a wide range of catalytic strategies, but it is not known whether artificial ribozymes are capable of the same ca…