Nature Chemical Biology

Nature Chemical Biology, Published online: 22 October 2024; doi:10.1038/s41589-024-01774-3Predicting small-molecule partitioning

Nature Chemical Biology, Published online: 22 October 2024; doi:10.1038/s41589-024-01767-2A cerium-dependent photoenzyme

Nature Chemical Biology, Published online: 22 October 2024; doi:10.1038/s41589-024-01769-0Molecular glue modulates mitochondria

Nature Chemical Biology, Published online: 22 October 2024; doi:10.1038/s41589-024-01773-4Forming folate-fortified rice

Nature Chemical Biology, Published online: 22 October 2024; doi:10.1038/s41589-024-01766-3Bridging the gap in protein targeting

Nature Chemical Biology, Published online: 18 October 2024; doi:10.1038/s41589-024-01754-7Predicting prospective drug-like molecules quickly and accurately is a considerable challenge for de novo drug design. An interactome-based deep …

Nature Chemical Biology, Published online: 17 October 2024; doi:10.1038/s41589-024-01752-9The paenilamicins are hybrid nonribosomal peptide–polyketide compounds that inhibit protein synthesis. Here the authors reveal that paenilamicins…

Nature Chemical Biology, Published online: 16 October 2024; doi:10.1038/s41589-024-01741-yDevelopment of a targeted protein degradation platform, methylarginine targeting chimera (MrTAC), enables arginine methylation-driven degradation…

Nature Chemical Biology, Published online: 16 October 2024; doi:10.1038/s41589-024-01748-5Fucosylation of host glycoproteins is revealed to sensitize cells to cholera intoxication while fucosylation of host glycolipids is protective. T…

Nature Chemical Biology, Published online: 15 October 2024; doi:10.1038/s41589-024-01743-wProkaryotic CRISPR–Cas systems are counteracted by phage-encoded anti-CRISPR elements, and how they protect themselves remains enigmatic. A study…