Molecular Cell
Stressed to death: Mitochondrial stress responses connect respiration and apoptosis in cancer
Publication date: 15 September 2022Source: Molecular Cell, Volume 82, Issue 18Author(s): Jacob M. Winter, Tarun Yadav, Jared Rutter
Molecular Cell
Mitotic DNA synthesis is caused by transcription-replication conflicts in BRCA2-deficient cells
Publication date: 15 September 2022Source: Molecular Cell, Volume 82, Issue 18Author(s): Florian J. Groelly, Rebecca A. Dagg, Michalis Petropoulos, Giacomo G. Rossetti, Birbal Prasad, Andreas Panagopoulos, Teressa Paulsen, Angeliki Karamichali, Samuel …
Molecular Cell
RAD51 protects human cells from transcription-replication conflicts
Publication date: 15 September 2022Source: Molecular Cell, Volume 82, Issue 18Author(s): Rahul Bhowmick, Mads Lerdrup, Sampath Amitash Gadi, Giacomo G. Rossetti, Manika I. Singh, Ying Liu, Thanos D. Halazonetis, Ian D. Hickson
Molecular Cell
SPT6 functions in transcriptional pause/release via PAF1C recruitment
Publication date: 15 September 2022Source: Molecular Cell, Volume 82, Issue 18Author(s): Yuki Aoi, Avani P. Shah, Sheetal Ganesan, Shimaa H.A. Soliman, Byoung-Kyu Cho, Young Ah Goo, Neil L. Kelleher, Ali Shilatifard
Molecular Cell
Chromatin jets define the properties of cohesin-driven <em>in vivo</em> loop extrusion
Publication date: Available online 30 September 2022Source: Molecular CellAuthor(s): Ya Guo, Ediem Al-Jibury, Rosalba Garcia-Millan, Konstantinos Ntagiantas, James W.D. King, Alex J. Nash, Niels Galjart, Boris Lenhard, Daniel Rueckert, Amanda G. Fisher…
Molecular Cell
“Stripe” transcription factors provide accessibility to co-binding partners in mammalian genomes
Publication date: 15 September 2022Source: Molecular Cell, Volume 82, Issue 18Author(s): Yongbing Zhao, Supriya V. Vartak, Andrea Conte, Xiang Wang, David A. Garcia, Evan Stevens, Seol Kyoung Jung, Kyong-Rim Kieffer-Kwon, Laura Vian, Timothy Stodola, F…
Molecular Cell
Endogenous ligand recognition and structural transition of a human PTH receptor
Publication date: 15 September 2022Source: Molecular Cell, Volume 82, Issue 18Author(s): Kazuhiro Kobayashi, Kouki Kawakami, Tsukasa Kusakizako, Hirotake Miyauchi, Atsuhiro Tomita, Kan Kobayashi, Wataru Shihoya, Keitaro Yamashita, Tomohiro Nishizawa, H…
Molecular Cell
TMUB1 is an endoplasmic reticulum-resident escortase that promotes the p97-mediated extraction of membrane proteins for degradation
Publication date: 15 September 2022Source: Molecular Cell, Volume 82, Issue 18Author(s): Linhan Wang, Jiqiang Li, Qingchen Wang, Man-Xi Ge, Jia Ji, Di Liu, Zhiyuan Wang, Yang Cao, Yaoyang Zhang, Zai-Rong Zhang
Molecular Cell
Structure of the RAF1-HSP90-CDC37 complex reveals the basis of RAF1 regulation
Publication date: 15 September 2022Source: Molecular Cell, Volume 82, Issue 18Author(s): Sara García-Alonso, Pablo Mesa, Laura de la Puente Ovejero, Gonzalo Aizpurua, Carmen G. Lechuga, Eduardo Zarzuela, Clara M. Santiveri, Manuel Sanclemente, Javier M…
Molecular Cell
Structural mechanism of endonucleolytic processing of blocked DNA ends and hairpins by Mre11-Rad50
Publication date: 15 September 2022Source: Molecular Cell, Volume 82, Issue 18Author(s): Fabian Gut, Lisa Käshammer, Katja Lammens, Joseph D. Bartho, Anna-Maria Boggusch, Erik van de Logt, Brigitte Kessler, Karl-Peter Hopfner