Department of Biochemistry

Microbiology, Virology & Host Pathogen Interaction, Molecular Biology, Cell Biology

Life Science Alliance

The cytochrome b carboxyl terminal region is necessary for mitochondrial complex III assembly

Mitochondrial bc1 complex from yeast has 10 subunits, but only cytochrome b (Cytb) subunit is encoded in the mitochondrial genome. Cytb has eight transmembrane helices containing two hemes b for electron transfer. Cbp3 and Cbp6 assist Cytb synthesis, …

By , 3 years ago
Life Science Alliance

Gut microbiota-derived short-chain fatty acids protect against the progression of endometriosis

Worldwide, ~196 million are afflicted with endometriosis, a painful disease in which endometrial tissue implants and proliferates on abdominal peritoneal surfaces. Theories on the origin of endometriosis remained inconclusive. Whereas up to 90% of wom…

By , 4 years ago
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