The thiosemicarbazone, DpC, broadly synergizes with multiple anti-cancer therapeutics and demonstrates temperature- and energy-dependent uptake by tumor cells

Publication date: Available online 15 April 2022Source: Biochimica et Biophysica Acta (BBA) – General SubjectsAuthor(s): Mahendiran Dharmasivam, Mahan Gholam Azad, Rizwana Afroz, Vera Richardson, Patric J. Jansson, Des R. Richardson

Pyridoxine non-responsive p.R336C mutation alters the molecular properties of cystathionine beta-synthase leading to severe homocystinuria phenotype

Publication date: July 2022Source: Biochimica et Biophysica Acta (BBA) – General Subjects, Volume 1866, Issue 7Author(s): Duaa W. Al-Sadeq, Angelos Thanassoulas, Zeyaul Islam, Prasanna Kolatkar, Nader Al-Dewik, Bared Safieh-Garabedian, Gheyath K. Nasra…