Charge engineering of the nucleic acid binding cleft of a thermostable HIV-1 reverse transcriptase reveals key interactions and a novel mechanism of RNase H inactivation

Publication date: Available online 1 August 2023Source: Journal of Molecular BiologyAuthor(s): Javier Martínez del Río, Nerea López-Carrobles, Jesús I. Mendieta-Moreno, Óscar Herrera-Chacón, Adrián Sánchez-Ibáñez, Jesús Mendieta, Luis Menéndez-Arias…