Genomics & Functional Genomics, Stem Cells, Chromatin & Epigenetics
HERVH-derived lncRNAs negatively regulate chromatin targeting and remodeling mediated by CHD7
Chd7 encodes an ATP-dependent chromatin remodeler which has been shown to target specific genomic loci and alter local transcription potentially by remodeling chromatin structure. De novo mutations in CHD7 are the major cause of CHARGE syndrome which …