Bioorganic Chemistry

Chemical synthesis and functional evaluation of the crayfish insulin-like androgenic gland factor

Publication date: May 2022Source: Bioorganic Chemistry, Volume 122Author(s): Hidekazu Katayama, Kenji Toyota, Haruna Tanaka, Tsuyoshi Ohira

By ScienceDirect Publication: Bioorganic Chemistry, 3 years ago

Discovery of new ERRγ agonists regulating dopaminergic neuronal phenotype in SH-SY5Y cells

Publication date: May 2022Source: Bioorganic Chemistry, Volume 122Author(s): Taewoo Kim, Hyo In Kim, Haejun Oh, Yoonsu Jeon, Hyeyoung Shin, Hyun Su Kim, Juhee Lim, Changjin Lim, Jakyung Yoo, Young-Ger Suh, Woo Sung Son, Hyun Jin Choi, Seok-Ho Kim

By ScienceDirect Publication: Bioorganic Chemistry, 3 years ago

Controlled microwave-assisted reactions: A facile synthesis of polyfunctionally substituted phthalazines as dual EGFR and PI3K inhibitors in CNS SNB-75 cell line

Publication date: May 2022Source: Bioorganic Chemistry, Volume 122Author(s): Maiiada Hassan Nazmy, Ramadan Ahmed Mekheimer, Mai E. Shoman, Mohamed Abo-Elsebaa, Mohamed Abd-Elmonem, Kamal Usef Sadek

By ScienceDirect Publication: Bioorganic Chemistry, 3 years ago

Bioorganic Chemistry

Discovery of novel microtubule stabilizers targeting taxane binding site by applying molecular docking, molecular dynamics simulation, and anticancer activity testing

Publication date: May 2022Source: Bioorganic Chemistry, Volume 122Author(s): Hui Zhang, Hua-Zhao Qi, Jun Mao, Hong-Rui Zhang, Qing-Qing Luo, Mei-Ling Hu, Chen Shen, Lan Ding

By ScienceDirect Publication: Bioorganic Chemistry, 3 years ago

Bioorganic Chemistry

Azaphilone derivatives with anti-inflammatory activity from the mangrove endophytic fungus Penicillium sclerotiorum ZJHJJ-18

Publication date: May 2022Source: Bioorganic Chemistry, Volume 122Author(s): Hongming Jiang, Runlin Cai, Zhenming Zang, Wencong Yang, Bo Wang, Ge Zhu, Jie Yuan, Zhigang She

By ScienceDirect Publication: Bioorganic Chemistry, 3 years ago

Bioorganic Chemistry

Pharmacophore optimization of imidazole chalcones to modulate microtubule dynamics

Publication date: May 2022Source: Bioorganic Chemistry, Volume 122Author(s): Endri Karaj, Samkeliso Dlamini, Radhika Koranne, Shaimaa H. Sindi, Lalith Perera, William R. Taylor, L.M. Viranga Tillekeratne

By ScienceDirect Publication: Bioorganic Chemistry, 3 years ago

Bioorganic Chemistry

HDAC1/MAO-B dual inhibitors against Alzheimer’s disease: Design, synthesis and biological evaluation of N-propargylamine-hydroxamic acid/o-aminobenzamide hybrids

Publication date: May 2022Source: Bioorganic Chemistry, Volume 122Author(s): Chuansheng Yao, Xiaoying Jiang, Rui Zhao, Zhichao Zhong, Jiamin Ge, Junlong Zhu, Xiang-Yang Ye, Yuanyuan Xie, Zhen Liu, Tian Xie, Renren Bai

By ScienceDirect Publication: Bioorganic Chemistry, 3 years ago

Bioorganic Chemistry

Escherichia coli tRNA 2-selenouridine synthase SelU selects its prenyl substrate to accomplish its enzymatic function

Publication date: May 2022Source: Bioorganic Chemistry, Volume 122Author(s): Patrycja Szczupak, Ewa Radzikowska-Cieciura, Katarzyna Kulik, Rafał Madaj, Małgorzata Sierant, Agnieszka Krakowiak, Barbara Nawrot

By ScienceDirect Publication: Bioorganic Chemistry, 3 years ago

Bioorganic Chemistry

Identification and molecular mechanism of a tri-peptide inhibitor targeting iNOS from duck embryo protein hydrolysates by experimental and bioinformatics studies

Publication date: May 2022Source: Bioorganic Chemistry, Volume 122Author(s): Yudi Peng, Lijun Bu, Xiaochun Zhang, Zhengmei Ji, Huadong Xie, Guizhao Liang

By ScienceDirect Publication: Bioorganic Chemistry, 3 years ago

Bioorganic Chemistry

Novel third-generation pyrimidines-based EGFR tyrosine kinase inhibitors targeting EGFR T790M mutation in advanced non-small cell lung cancer

Publication date: May 2022Source: Bioorganic Chemistry, Volume 122Author(s): Baijiao An, Jian Liu, Yangyang Fan, Wenyan Nie, Chunhua Yang, Han Yao, Wei Li, Yin Zhang, Xingshu Li, Geng Tian

By ScienceDirect Publication: Bioorganic Chemistry, 3 years ago

Bioorganic Chemistry

Bioorganic Chemistry

Chemical synthesis and functional evaluation of the crayfish insulin-like androgenic gland factor

Bioorganic Chemistry

Discovery of new ERRγ agonists regulating dopaminergic neuronal phenotype in SH-SY5Y cells

Bioorganic Chemistry

Controlled microwave-assisted reactions: A facile synthesis of polyfunctionally substituted phthalazines as dual EGFR and PI3K inhibitors in CNS SNB-75 cell line

Bioorganic Chemistry

Discovery of novel microtubule stabilizers targeting taxane binding site by applying molecular docking, molecular dynamics simulation, and anticancer activity testing

Bioorganic Chemistry

Azaphilone derivatives with anti-inflammatory activity from the mangrove endophytic fungus <em>Penicillium sclerotiorum</em> ZJHJJ-18

Bioorganic Chemistry

Pharmacophore optimization of imidazole chalcones to modulate microtubule dynamics

Bioorganic Chemistry

HDAC1/MAO-B dual inhibitors against Alzheimer’s disease: Design, synthesis and biological evaluation of <em>N</em>-propargylamine-hydroxamic acid/<em>o</em>-aminobenzamide hybrids

Bioorganic Chemistry

<em>Escherichia coli</em> tRNA 2-selenouridine synthase SelU selects its prenyl substrate to accomplish its enzymatic function

Bioorganic Chemistry

Identification and molecular mechanism of a tri-peptide inhibitor targeting iNOS from duck embryo protein hydrolysates by experimental and bioinformatics studies

Bioorganic Chemistry

Novel third-generation pyrimidines-based EGFR tyrosine kinase inhibitors targeting EGFR T790M mutation in advanced non-small cell lung cancer