Bioorganic Chemistry

A novel ratiometric fluorescent probe for the detection and imaging of cysteine in living cells

Publication date: October 2022Source: Bioorganic Chemistry, Volume 127Author(s): Cheng Zheng, Xiaoqin Zhou, Huizhe Wang, Min Ji, Peng Wang

By ScienceDirect Publication: Bioorganic Chemistry, 2 years ago

Hexa-substituted cyclotriphosphazene derivatives containing hetero-ring chalcones: Synthesis, in vitro cytotoxic activity and their DNA damage determination

Publication date: October 2022Source: Bioorganic Chemistry, Volume 127Author(s): Asiye Beytur, Çiğdem Tekin, Eray Çalışkan, Suat Tekin, Kenan Koran, Ahmet Orhan Görgülü, Süleyman Sandal

By ScienceDirect Publication: Bioorganic Chemistry, 2 years ago

Discovery of novel 4-arylamino-quinazoline derivatives as EGFRL858R/T790M inhibitors with the potential to inhibit the non-small cell lung cancers

Publication date: October 2022Source: Bioorganic Chemistry, Volume 127Author(s): Wenhui Gan, Caolin Wang, Qingshan Pan, Yuzhen Li, Yuping Guo, Dang Fan, Yuting Peng, Zixuan Rao, Shan Xu, Pengwu Zheng, Wufu Zhu

By ScienceDirect Publication: Bioorganic Chemistry, 2 years ago

SAR study culminates in a series of HDAC6 selective inhibitors featuring Schisandrin C-analogous Cap as potential immunomodulatory agents for cancer therapy

Publication date: October 2022Source: Bioorganic Chemistry, Volume 127Author(s): Qiangqiang Tao, Wei Wei, Xiaoqing Lv, Jian Guo, Yaotian Tao, Mingming Zhang, Ge He, Zhi Li, Shuangying Gui, Xiaodong Ma

By ScienceDirect Publication: Bioorganic Chemistry, 2 years ago

Bioorganic Chemistry

Design and synthesis of novel benzoazoninone derivatives as potential CBSIs and apoptotic inducers: In Vitro, in Vivo, molecular docking, molecular dynamics, and SAR studies

Publication date: October 2022Source: Bioorganic Chemistry, Volume 127Author(s): Mohamed M. Hammouda, Ayman Abo Elmaaty, Mohamed S. Nafie, Marwa Abdel-Motaal, Noha S. Mohamed, Mohamed A. Tantawy, Amany Belal, Radwan Alnajjar, Wagdy M. Eldehna, Ahmed A….

By ScienceDirect Publication: Bioorganic Chemistry, 2 years ago

Bioorganic Chemistry

Activatable fluorescence molecular imaging and anti-tumor effects investigation of GSH-sensitive BRD4 ligands

Publication date: Available online 25 January 2022Source: Bioorganic ChemistryAuthor(s): Hang Zhang, Mingliang Zhang, Yujie Zhang, Han Wang, Linnan Zhao, Haiwei Xu

By ScienceDirect Publication: Bioorganic Chemistry, 3 years ago

Bioorganic Chemistry

The in vitro and in vivo study of a pyrazole derivative, J-1063, as a novel anti-liver fibrosis agent: Synthesis, biological evaluation, and mechanistic analysis

Publication date: May 2022Source: Bioorganic Chemistry, Volume 122Author(s): Guang-Hao Zheng, Jian Liu, Fang Yan Guo, Zhi-Hong Zhang, Yin-Jing Jiang, Yong-Ce Lin, Xiao-Qi Lan, Jie Ren, Yan-Ling Wu, Ji-Xing Nan, Cheng Hua Jin, Li-Hua Lian

By ScienceDirect Publication: Bioorganic Chemistry, 3 years ago

Bioorganic Chemistry

Palladium catalyzed migratory heck coupling of arteannuin B and boronic acids: An approach towards the synthesis of antiproliferative agents in breast and lung cancer cells

Publication date: May 2022Source: Bioorganic Chemistry, Volume 122Author(s): Javeed Ur Rasool, Khalid Bashir Mir, Majeed Shaikh, Aabid H. Bhat, Yedukondalu Nalli, Anam Khalid, Syed Mudabir Ahmad, Anindya Goswami, Asif Ali

By ScienceDirect Publication: Bioorganic Chemistry, 3 years ago

Bioorganic Chemistry

Exploration of novel VEGFR2 tyrosine kinase inhibitors via design and synthesis of new alkylated indolyl-triazole Schiff bases for targeting breast cancer

Publication date: May 2022Source: Bioorganic Chemistry, Volume 122Author(s): Mohamed S. Nafie, Ahmed T.A. Boraei

By ScienceDirect Publication: Bioorganic Chemistry, 3 years ago

Bioorganic Chemistry

Anti-neuroinflammatory effects in vitro and in vivo, and chemical profile of Jatropha curcas L

Publication date: May 2022Source: Bioorganic Chemistry, Volume 122Author(s): Yingjie Wang, Di Zhou, Qingqi Meng, Libin Xu, Xiaohu Yao, Xue Ni, Haihui Xie, Guojiang Wu, Gang Chen, Yue Hou, Ning Li

By ScienceDirect Publication: Bioorganic Chemistry, 3 years ago

Bioorganic Chemistry

Bioorganic Chemistry

A novel ratiometric fluorescent probe for the detection and imaging of cysteine in living cells

Bioorganic Chemistry

Hexa-substituted cyclotriphosphazene derivatives containing hetero-ring chalcones: Synthesis, <em>in vitro</em> cytotoxic activity and their DNA damage determination

Bioorganic Chemistry

Discovery of novel 4-arylamino-quinazoline derivatives as EGFR<sup>L858R/T790M</sup> inhibitors with the potential to inhibit the non-small cell lung cancers

Bioorganic Chemistry

SAR study culminates in a series of HDAC6 selective inhibitors featuring Schisandrin C-analogous Cap as potential immunomodulatory agents for cancer therapy

Bioorganic Chemistry

Design and synthesis of novel benzoazoninone derivatives as potential CBSIs and apoptotic inducers: <em>In Vitro</em>, <em>in Vivo</em>, molecular docking, molecular dynamics, and SAR studies

Bioorganic Chemistry

Activatable fluorescence molecular imaging and anti-tumor effects investigation of GSH-sensitive BRD4 ligands

Bioorganic Chemistry

The <em>in vitro</em> and <em>in vivo</em> study of a pyrazole derivative, J-1063, as a novel anti-liver fibrosis agent: Synthesis, biological evaluation, and mechanistic analysis

Bioorganic Chemistry

Palladium catalyzed migratory heck coupling of arteannuin B and boronic acids: An approach towards the synthesis of antiproliferative agents in breast and lung cancer cells

Bioorganic Chemistry

Exploration of novel VEGFR2 tyrosine kinase inhibitors <em>via</em> design and synthesis of new alkylated indolyl-triazole Schiff bases for targeting breast cancer

Bioorganic Chemistry

Anti-neuroinflammatory effects <em>in vitro</em> and <em>in vivo</em>, and chemical profile of <em>Jatropha curcas</em> L