Bioorganic Chemistry
Recent developments in promiscuous enzymatic reactions for carbon–nitrogen bond formation
Publication date: October 2022Source: Bioorganic Chemistry, Volume 127Author(s): Hui Xia, Jinsong Song, Changfan Li, Feng Xue
Bioorganic Chemistry
Discovery of a novel class of benzoxazole derivatives as histamine H<sub>3</sub> receptor ligands for the treatment of neuropathic pain
Publication date: October 2022Source: Bioorganic Chemistry, Volume 127Author(s): Ziying Li, Xinyi Xiao, Yulin Xue, Huiling Zhou, Chaonan Huang, Mo Zhu, Tao Zhuang, Yin Chen, Ling Huang
Bioorganic Chemistry
Imidazo[4,5-<em>b</em>]pyridine derived tubulin polymerization inhibitors: Design, synthesis, biological activity <em>in vitro</em> and computational analysis
Publication date: October 2022Source: Bioorganic Chemistry, Volume 127Author(s): Ida Boček, Lucija Hok, Leentje Persoons, Dirk Daelemans, Robert Vianello, Marijana Hranjec
Bioorganic Chemistry
Design, synthesis, <em>in vitro,</em> and <em>in silico</em> enzymatic evaluations of thieno[2,3-<em>b</em>]quinoline-hydrazones as novel inhibitors for α-glucosidase
Publication date: October 2022Source: Bioorganic Chemistry, Volume 127Author(s): Milad Noori, Mryam Rastak, Mohammad Halimi, Minoo Khalili Ghomi, Mrjan Mollazadeh, Maryam Mohammadi-Khanaposhtani, Mohammad Hosein Sayahi, Zahra Rezaei, Somayeh Mojtabavi,…
Bioorganic Chemistry
Isolation, derivatization, <em>in-vitro</em>, and <em>in-silico</em> studies of potent butyrylcholinesterase inhibitors from <em>Berberis parkeriana</em> Schneid
Publication date: October 2022Source: Bioorganic Chemistry, Volume 127Author(s): Rabia Ali, Atia-tul-Wahab, Sheeba Wajid, Maria Aqeel Khan, Sammer Yousuf, Muniza Shaikh, Gul Hassan Laghari, Atta-ur Rahman, M. Iqbal Choudhary
Bioorganic Chemistry
Development of a series of novel Mcl-1 inhibitors bearing an indole carboxylic acid moiety
Publication date: October 2022Source: Bioorganic Chemistry, Volume 127Author(s): Hongguang Deng, Min Huang, Hui Liu, Hong Zhang, Liang Liu, Bensheng Gao, Xianlu Li, Jinbo Li, Qun Niu, Zhenwei Zhang, Shenglin Luan, Jingyi Zhang, Yongkui Jing, Dan Liu, L…
Bioorganic Chemistry
Menisperdaurines A-W, structurally diverse isoquinoline alkaloids from <em>Menispermum dauricum</em> and their dopamine D1 receptor activities
Publication date: October 2022Source: Bioorganic Chemistry, Volume 127Author(s): Hong-Li Wei, Yao-Peng Zhao, Ji-Xia Wang, Yang Han, Hao Li, Han Zhou, Tao Hou, Chang-Jian Wang, Yu-Min Yao, Xiu-Li Zhang, Yan-Fang Liu, Xin-Miao Liang
Bioorganic Chemistry
Applications of “linkers” in fragment-based drug design
Publication date: October 2022Source: Bioorganic Chemistry, Volume 127Author(s): Xin Wu, Yuan Zhang, Songbin Liu, Chang Liu, Guotao Tang, Xuan Cao, Xiaoyong Lei, Junmei Peng
Bioorganic Chemistry
Antidiabetic lanostane triterpenoids from the fruiting bodies of <em>Ganoderma weberianum</em>
Publication date: October 2022Source: Bioorganic Chemistry, Volume 127Author(s): Li Yang, De-Xian Kong, Na Xiao, Qing-Yun Ma, Qing-Yi Xie, Jiao-Cen Guo, Chun Ying Deng, Hai-Xia Ma, Yan Hua, Hao-Fu Dai, You-Xing Zhao
Bioorganic Chemistry
Violacein switches off low molecular weight tyrosine phosphatase and rewires mitochondria in colorectal cancer cells
Publication date: October 2022Source: Bioorganic Chemistry, Volume 127Author(s): Alessandra V.S. Faria, Emanuella M.B. Fonseca, Patrícia de S. Fernandes-Oliveira, Tanes I. de Lima, Stefano P. Clerici, Giselle Z. Justo, Leonardo R. Silveira, Nelson Durá…