Identification of a novel nitroflavone-based scaffold for designing mutant-selective EGFR tyrosine kinase inhibitors targeting T790M and C797S resistance in advanced NSCLC

Publication date: December 2022Source: Bioorganic Chemistry, Volume 129Author(s): Minnelli Cristina, Laudadio Emiliano, Sorci Leonardo, Sabbatini Giulia, Galeazzi Roberta, Amici Adolfo, Semrau S. Marta, Storici Paola, Rinaldi Samuele, Stipa Pierluigi, …