In-situ construction of fluorescent probes for hydrogen peroxide detection in mitochondria and lysosomes with on-demand modular assembling and double turn-on features

Publication date: January 2023Source: Bioorganic Chemistry, Volume 130Author(s): Gang Feng, Peng Zhai, Zhengzheng Li, Miaozhuang Fan, Yihang Jiang, Nan Qiao, Ribao Chen, Shuo Tang, Zhourui Xu, Xiaomei Wang, Guimiao Lin, Chengbin Yang, Ming Ying, Biqin …

Based on 2-(difluoromethyl)-1-[4,6-di(4-morpholinyl)-1,3,5-triazin-2-yl]-1<em>H</em>-benzimidazole (ZSTK474), design, synthesis and biological evaluation of novel PI3K<em>α</em> selective inhibitors

Publication date: January 2023Source: Bioorganic Chemistry, Volume 130Author(s): Yu Wang, Yajing Liu, Tingjie Ge, Jiechun Tang, Shihui Wang, Zhanfeng Gao, Jiaxu Chen, Jundong Xu, Ping Gong, Yanfang Zhao, Jiuyu Liu, Yunlei Hou