Discovery of <em>N</em>-methylbenzo[<em>d</em>]oxazol-2-amine as new anthelmintic agent through scalable protocol for the synthesis of <em>N</em>-alkylbenzo[<em>d</em>]oxazol-2-amine and <em>N</em>-alkylbenzo[<em>d</em>]thiazol-2-amine derivatives

Publication date: Available online 25 November 2022Source: Bioorganic ChemistryAuthor(s): Pavitra Laohapaisan, Onrapak Reamtong, Jumreang Tummatorn, Charnsak Thongsornkleeb, Urusa Thaenkham, Poom Adisakwattana, Somsak Ruchirawat

Design, synthesis, biological activity evaluation and structure-activity relationships of new steroidal aromatase inhibitors. The case of C-ring and 7β substituted steroids

Publication date: Available online 23 November 2022Source: Bioorganic ChemistryAuthor(s): Fernanda M. F. Roleira, Saul C. Costa, Ana R. Gomes, Carla L. Varela, Cristina Amaral, Tiago V. Augusto, Georgina Correia-da-Silva, Isabella Romeo, Giosuè Costa, …